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Ranked #530

1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.

Desk Score 46/100 (C) · Verified July 2026

Visit 1st OptimalAssume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way.

Is 1st Optimal legit?

Only what 1st Optimal publishes and what we could check ourselves — nothing inferred. See the methodology.

Certification
On third-party certification, the site doesn't say.
Where it ships
The site doesn't say which states it serves.
Last checked
July 2026, against 1st Optimal's own pages.
Published price
1st Optimal publishes no price we could read; the figure comes after the intake.
What it sells
Compounded medication only, injectable and oral routes.
Licensing & trust
65/100 on the scored dimension of that name — one of the six in our published methodology.

Checks out on everything except cost: 1st Optimal publishes no monthly figure, so what you will pay is only knowable after the intake.

What does 1st Optimal cost?

Each figure exactly as 1st Optimal publishes it, with the condition attached to it spelled out.

Semaglutide

Not listed on 1st Optimal's site (checked July 2026)

Tirzepatide

Not listed on 1st Optimal's site (checked July 2026)

There is no published figure to compare: 1st Optimal does not put a price on the pages we read, so the cost is only knowable once the intake is finished.

All figures as published on 1st Optimal's own site and read in July 2026. Prices change — confirm before you order.

Semaglutide
Not listed on 1st Optimal's site (checked July 2026)
Tirzepatide
Not listed on 1st Optimal's site (checked July 2026)
Coverage
Not listed on 1st Optimal's site (checked July 2026)
Brand-name
Compounded only

Line 1st Optimal up against its closest alternatives. Or go one-on-one: 1st Optimal vs CoreAge Rx. Because 1st Optimal dispenses compounded medication, it’s worth understanding whether compounded GLP-1 is legit and safe.

Desk Score breakdown

Each of the six scored dimensions. See the methodology.

Price transparency20/100
State access24/100
Molecule range77/100
Onboarding speed40/100
Support responsiveness82/100
Licensing & trust65/100

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where points come off

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

The bottom line — C

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

1st Optimal ranks #530 of 542 providers scored — see #1, CoreAge Rx here.

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Pricing and verification reflect 1st Optimal's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.

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