Certification: We found no LegitScript certification displayed when we read the site. Where it ships: 49 states (its own banner says all 50), as published on the site. Last checked: September 2026, against Rx.com's own pages. Published price: Rx.com publishes a figure for semaglutide and tirzepatide — the qualifiers are in "What does Rx.com cost?" below. What it sells: Compounded medication only, injectable route only. Licensing & trust: 88/100 on the scored dimension of that name — one of the six in our published methodology. Checks out on the facts we can verify: a flat month-to-month price, coverage published nationwide, and a dated check against the company's own pages.

C+78/100

Desk Score

Ranked #99

Rx.com

Q: What does Rx.com cost?

Semaglutide: $175/mo month-to-month (compounded; $146 only on a 6-month prepay). That is a flat month-to-month rate: $175 a month, with no plan term attached to the figure. Median semaglutide figure across this site: $190 a month, of 164 providers with a published month-to-month price and a check date. Rx.com's $175 a month sits $15 below it. Tirzepatide: $285/mo month-to-month (compounded; $259 only on a 6-month prepay). That is a flat month-to-month rate: $285 a month, with no plan term attached to the figure. Median tirzepatide figure across this site: $264 a month, of 163 providers with a published month-to-month price and a check date. Rx.com's $285 a month sits $21 above it. All figures as published on Rx.com's own site and read in September 2026. Prices change — confirm before you order.

Names the pharmacy that fills the vial, with a street address, and prints "No automatic renewals" on the plan card — then advertises another drug's prepay rate.

Desk Score 78/100 (C+) · Verified September 2026

Visit Rx.com ↗Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way.

Is Rx.com legit?

Only what Rx.com publishes and what we could check ourselves — nothing inferred. See the methodology.

Certification: We found no LegitScript certification displayed when we read the site.
Where it ships: 49 states (its own banner says all 50), as published on the site.
Last checked: September 2026, against Rx.com's own pages.
Published price: Rx.com publishes a figure for semaglutide and tirzepatide — the qualifiers are in "What does Rx.com cost?" below.
What it sells: Compounded medication only, injectable route only.
Licensing & trust: 88/100 on the scored dimension of that name — one of the six in our published methodology.

Checks out on the facts we can verify: a flat month-to-month price, coverage published nationwide, and a dated check against the company's own pages.

What does Rx.com cost?

Each figure exactly as Rx.com publishes it, with the condition attached to it spelled out.

Semaglutide

$175/mo month-to-month (compounded; $146 only on a 6-month prepay)

That is a flat month-to-month rate: $175 a month, with no plan term attached to the figure.

Median semaglutide figure across this site: $190 a month, of 164 providers with a published month-to-month price and a check date. Rx.com's $175 a month sits $15 below it.

Tirzepatide

$285/mo month-to-month (compounded; $259 only on a 6-month prepay)

That is a flat month-to-month rate: $285 a month, with no plan term attached to the figure.

Median tirzepatide figure across this site: $264 a month, of 163 providers with a published month-to-month price and a check date. Rx.com's $285 a month sits $21 above it.

All figures as published on Rx.com's own site and read in September 2026. Prices change — confirm before you order.

Semaglutide: $175/mo
Tirzepatide: $285/mo
Coverage: 49 states (its own banner says all 50)
Brand-name: Compounded only
Verification: Prices as published on Rx.com's site — verified september 2026. Each figure's full condition is in “What does Rx.com cost?” below.

Weigh Rx.com against the full ranked field on the best semaglutide providers ranking, or line it up against its closest alternatives. Or go one-on-one: Rx.com vs CoreAge Rx. Because Rx.com dispenses compounded medication, it’s worth understanding whether compounded GLP-1 is legit and safe.

Desk Score breakdown

Each of the six scored dimensions. See the methodology.

Price transparency74/100

State access82/100

Molecule range66/100

Onboarding speed88/100

Support responsiveness76/100

Licensing & trust88/100

What we like

"No automatic renewals" is printed under the plan card itself rather than buried in terms.
Names Manifest Pharmacy in Greer, South Carolina, with a full street address, and names MD Integrations as the provider network — on the same page as the price.
One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included.
A provider who declines to prescribe does not charge you for medication.

Where points come off

The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285.
The plan page says 49 states served while the banner on the same site says all 50 — the site contradicts itself on coverage.
No oral route and no FDA-approved brand option.
LegitScript certification is claimed in the footer; we did not verify who holds the id.

The bottom line — C+

Best for: Someone who will judge it by the plan card rather than the banner, and who wants no auto-renewal and a named pharmacy.

Rx.com ranks #99 of 542 providers scored — see #1, CoreAge Rx here.

Visit Rx.com ↗

Pricing and verification reflect Rx.com's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on Rx.com's site. Not medical advice; see our disclosure.

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