Head-to-head dispatch
Signos vs yourEra
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…
Marked down on: Compounded GLP-1s are not FDA-approved finished products
Desk Score
A rare compounded desk that publishes its pricing outright — both molecules plus a NAD+ and microdosing menu, across all 50 states.
Marked down on: Compounded only — not FDA-approved and not equivalent to brand Wegovy/Ozempic or Zepbound; availability can tighten as brand shortages resolve
yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Signos
62/100
C
yourEra
84/100
B
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Signos | yourEra |
|---|---|---|
| Semaglutide | $199/mo (6-month plan, compounded) | $199/mo |
| Tirzepatide | $199/mo (starting dose, compounded) | $299/mo |
| Coverage | Coverage not published | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Readers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app. | Patients who want transparent, upfront pricing on both semaglutide and tirzepatide and value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes. |
| Desk Score | 62/100C | 84/100B |
The verdict
Desk pick — yourErayourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.
Choose Signos if…
Readers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
$199/mo (6-month plan, compounded) sema · $199/mo (starting dose, compounded) tirz · Coverage not published
Choose yourEra if…
Patients who want transparent, upfront pricing on both semaglutide and tirzepatide and value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.
$199/mo sema · $299/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Signos · yourEra.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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- yourEra vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.