Certification: On third-party certification, the site doesn't say. Where it ships: The site doesn't say which states it serves. Last checked: July 2026, against Signos's own pages. Published price: Signos publishes a figure for semaglutide and tirzepatide — the qualifiers are in "What does Signos cost?" below. What it sells: Compounded medication only, injectable route only. Licensing & trust: 78/100 on the scored dimension of that name — one of the six in our published methodology. Checks out as far as the figures go, with one caveat: every price Signos publishes carries a condition, so the number on the site is not the monthly bill.

C62/100

Desk Score

Ranked #344

Signos

Q: What does Signos cost?

Semaglutide: $199/mo (6-month plan, compounded). That is a prepay rate: $199 a month applies only if the whole term is paid up front, so the charge on your card is larger than the monthly number. Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for semaglutide — only flat month-to-month rates compete there. Tirzepatide: $199/mo (starting dose, compounded). That is a starting figure, not the price at every dose: $199 a month is the lowest rung, and the cost rises from there. Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for tirzepatide — only flat month-to-month rates compete there. All figures as published on Signos's own site and read in July 2026. Prices change — confirm before you order.

Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app.

Desk Score 62/100 (C) · Verified July 2026

Visit Signos ↗Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way.

Is Signos legit?

Only what Signos publishes and what we could check ourselves — nothing inferred. See the methodology.

Certification: On third-party certification, the site doesn't say.
Where it ships: The site doesn't say which states it serves.
Last checked: July 2026, against Signos's own pages.
Published price: Signos publishes a figure for semaglutide and tirzepatide — the qualifiers are in "What does Signos cost?" below.
What it sells: Compounded medication only, injectable route only.
Licensing & trust: 78/100 on the scored dimension of that name — one of the six in our published methodology.

Checks out as far as the figures go, with one caveat: every price Signos publishes carries a condition, so the number on the site is not the monthly bill.

What does Signos cost?

Each figure exactly as Signos publishes it, with the condition attached to it spelled out.

Semaglutide

$199/mo (6-month plan, compounded)

That is a prepay rate: $199 a month applies only if the whole term is paid up front, so the charge on your card is larger than the monthly number.

Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for semaglutide — only flat month-to-month rates compete there.

Tirzepatide

$199/mo (starting dose, compounded)

That is a starting figure, not the price at every dose: $199 a month is the lowest rung, and the cost rises from there.

Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for tirzepatide — only flat month-to-month rates compete there.

All figures as published on Signos's own site and read in July 2026. Prices change — confirm before you order.

Semaglutide: $199/mo6-month prepay
Tirzepatide: From $199/molowest dose rung
Coverage: Not listed on Signos's site (checked July 2026)
Brand-name: Compounded only
Verification: Prices as published on Signos's site — verified july 2026. Each figure's full condition is in “What does Signos cost?” below.

Weigh Signos against the full ranked field on the best semaglutide providers ranking, or line it up against its closest alternatives. Or go one-on-one: Signos vs CoreAge Rx. Because Signos dispenses compounded medication, it’s worth understanding whether compounded GLP-1 is legit and safe.

Desk Score breakdown

Each of the six scored dimensions. See the methodology.

Price transparency68/100

State access24/100

Molecule range66/100

Onboarding speed72/100

Support responsiveness82/100

Licensing & trust78/100

What we like

Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
Free rapid shipping; HSA/FSA eligible
Real-time glucose insights and app coaching to help sustain results after GLP-1

Where points come off

Compounded GLP-1s are not FDA-approved finished products
Headline price is a 6-month-program rate, not month-to-month
Only semaglutide is shown in the program; tirzepatide availability is not confirmed
Compounding pharmacy partner and state availability are not published on the landing page

The bottom line — C

Best for: Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.

Signos ranks #344 of 542 providers scored — see #1, CoreAge Rx here.

Visit Signos ↗

Pricing and verification reflect Signos's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on Signos's site. Not medical advice; see our disclosure.

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