Head-to-head comparison
CoreAge Rx vs Signos
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
$99/mo (12-month prepay) sema · $149/mo (12-month prepay) tirz · Verified August 2026
Marked down on: The advertised $99/$149 per month is a 12-month plan paid in full ($1,188 / $1,788 up front); no month-to-month price is published
Desk Score
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app.
$199/mo (6-month prepay) sema · From $199/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Compounded GLP-1s are not FDA-approved finished products
CoreAge Rx takes this head-to-head with the higher Desk Score, 94/100 (A) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
CoreAge Rx
94/100
A
Signos
62/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | CoreAge Rx | Signos |
|---|---|---|
| Semaglutide | $99/mo12-month prepay$99/mo only as a 12-month plan paid in full ($1,188 in one charge); the lander says "starting at, based on a 12-month plan paid in full"; no month-to-month price is published; same price at every dose; compounded injectable | $199/mo6-month prepay$199/mo (6-month plan, compounded) |
| Tirzepatide | $149/mo12-month prepay$149/mo only as a 12-month plan paid in full ($1,788 in one charge); no month-to-month price is published; same price at every dose; compounded injectable | From $199/molowest dose rung$199/mo (starting dose, compounded) |
| Coverage | All 50 states | Not listed on Signos's site (checked July 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who can prepay a year and wants one dose-independent price with full nationwide reach. | Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app. |
| Desk Score | 94/100A | 62/100C |
The verdict
Desk pick — CoreAge RxCoreAge Rx takes this head-to-head with the higher Desk Score, 94/100 (A) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.
Choose CoreAge Rx if…
Anyone who can prepay a year and wants one dose-independent price with full nationwide reach.
$99/mo (12-month prepay) sema · $149/mo (12-month prepay) tirz · All 50 states
Choose Signos if…
Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
$199/mo (6-month prepay) sema · From $199/mo (lowest dose rung) tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: CoreAge Rx · Signos.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.