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Head-to-head dispatch

Signos vs Strut Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #281
Signos

Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…

vs
Dispatch #3Desk pick
Strut Health

The same molecule as a lozenge or an injection at the same price — the only place on this board where the needle is genuinely optional.

Strut Health takes this head-to-head with the higher Desk Score, 88/100 (B+) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Signos

62/100

C

Overall

Strut Health

88/100

B+

Price transparency

68
93

State access

24
88

Molecule range

66
94

Onboarding speed

72
90

Support responsiveness

82
78

Licensing & trust

78
88

The spec sheet

FieldSignosStrut Health
Semaglutide$199/mo (6-month plan, compounded)From $99/mo sublingual, $149/mo injectable
Tirzepatide$199/mo (starting dose, compounded)From $199/mo either route
CoverageCoverage not published49 states (not Arkansas)
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyYes
Best forReaders who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.People whose real objection is the needle rather than the medicine, and who want every route priced before signing up.
Desk Score62/100C88/100B+

The verdict

Desk pick — Strut Health

Strut Health takes this head-to-head with the higher Desk Score, 88/100 (B+) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.

Choose Signos if…

Readers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.

$199/mo (6-month plan, compounded) sema · $199/mo (starting dose, compounded) tirz · Coverage not published

Choose Strut Health if…

People whose real objection is the needle rather than the medicine, and who want every route priced before signing up.

From $99/mo sublingual, $149/mo injectable sema · From $199/mo either route tirz · 49 states (not Arkansas)

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Signos · Strut Health.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.