Head-to-head dispatch
Ondra Health vs Signos
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Near-rock-bottom pricing paired with brand access and 50-state reach — a value standout a budget-first reader may rank #1.
Desk Score
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…
Ondra Health takes this head-to-head with the higher Desk Score, 90/100 (A−) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Ondra Health
90/100
A−
Signos
62/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Ondra Health | Signos |
|---|---|---|
| Semaglutide | $93/mo | $199/mo (6-month plan, compounded) |
| Tirzepatide | $166/mo | $199/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name | Yes | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Cost-conscious patients who still want brand-name capability and nationwide coverage. | Readers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app. |
| Desk Score | 90/100A− | 62/100C |
The verdict
Desk pick — Ondra HealthOndra Health takes this head-to-head with the higher Desk Score, 90/100 (A−) against 62/100 (C) for Signos. Signos still holds its ground where its strengths line up with yours.
Choose Ondra Health if…
Cost-conscious patients who still want brand-name capability and nationwide coverage.
$93/mo sema · $166/mo tirz · All 50 states
Choose Signos if…
Readers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
$199/mo (6-month plan, compounded) sema · $199/mo (starting dose, compounded) tirz · Coverage not published
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Ondra Health · Signos.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Ondra Health vs CoreAge Rx
- Signos vs Vaylen
- Ondra Health vs Strut Health
- Signos vs Invigor Medical
- Ondra Health vs Vytora Health
- Signos vs Sesame Care
Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.