Head-to-head comparison
OnlyRx vs Shed
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
OnlyRx is a cash-pay GLP-1 telehealth platform offering compounded semaglutide and tirzepatide in both injection and oral disintegrating tablet (ODT) forms — an uncommon needle-free option.
$179/mo (promo rate) sema · From $249/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Promo pricing ($179 semaglutide injection) is prominent, but post-promo maintenance pricing isn't shown
Desk Score
Widest formulation spread in the ranking — injection, liquid drops, lozenges and a daily oral pill, plus a real brand Zepbound lane.
$199/mo sema · $299/mo tirz · Verified August 2026
Marked down on: The advertised "as low as $239" tirzepatide rate needs a twelve-month commitment — month-to-month is $299
Shed takes this head-to-head with the higher Desk Score, 88/100 (B+) against 65/100 (C) for OnlyRx. OnlyRx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
OnlyRx
65/100
C
Shed
88/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | OnlyRx | Shed |
|---|---|---|
| Semaglutide | $179/mopromo rate$179/mo (starting dose, promotional rate, compounded) | $199/mo$199/mo month-to-month ($179/mo on the 6-month plan, $159/mo on the 12-month plan — both carry a minimum term whose shipped cycles are non-refundable) |
| Tirzepatide | From $249/molowest dose rung$249/mo (starting dose, compounded) | $299/mo$299/mo month-to-month ($269/mo on the 6-month plan, $239/mo on the 12-month plan — both carry a minimum term whose shipped cycles are non-refundable) |
| Coverage | Not listed on OnlyRx's site (checked July 2026) | All 50 states (no state list is published on the site) |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Compounded GLP-1 in oral-tablet and injection with named prescribers. | People who want a needle-free route or a brand-name option without leaving one provider. |
| Desk Score | 65/100C | 88/100B+ |
The verdict
Desk pick — ShedShed takes this head-to-head with the higher Desk Score, 88/100 (B+) against 65/100 (C) for OnlyRx. OnlyRx still holds its ground where its strengths line up with yours.
Choose OnlyRx if…
Compounded GLP-1 in oral-tablet and injection with named prescribers.
$179/mo (promo rate) sema · From $249/mo (lowest dose rung) tirz
Choose Shed if…
People who want a needle-free route or a brand-name option without leaving one provider.
$199/mo sema · $299/mo tirz · All 50 states (no state list is published on the site)
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: OnlyRx · Shed.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs OnlyRx
- CoreAge Rx vs Shed
- OnlyRx vs Vaylen
- Shed vs Vaylen
- OnlyRx vs Semaglutide Online
- Curex vs Shed
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.