Head-to-head comparison
OnlyRx vs Semaglutide Online
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
OnlyRx is a cash-pay GLP-1 telehealth platform offering compounded semaglutide and tirzepatide in both injection and oral disintegrating tablet (ODT) forms — an uncommon needle-free option.
$179/mo (promo rate) sema · From $249/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Promo pricing ($179 semaglutide injection) is prominent, but post-promo maintenance pricing isn't shown
Desk Score
Semaglutide Online is a LegitScript-certified telehealth platform prescribing compounded and brand-name GLP-1/GIP medications nationwide (excluding Alabama).
$199/mo sema · $299/mo tirz · Verified July 2026
Marked down on: No labs or clinical monitoring disclosed — blood work requirements not mentioned anywhere on site
Semaglutide Online takes this head-to-head with the higher Desk Score, 88/100 (B+) against 65/100 (C) for OnlyRx. OnlyRx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
OnlyRx
65/100
C
Semaglutide Online
88/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | OnlyRx | Semaglutide Online |
|---|---|---|
| Semaglutide | $179/mopromo rate$179/mo (starting dose, promotional rate, compounded) | $199/mo$199/mo (all doses, compounded) |
| Tirzepatide | From $249/molowest dose rung$249/mo (starting dose, compounded) | $299/mo$299/mo (all doses, compounded) |
| Coverage | Not listed on OnlyRx's site (checked July 2026) | All 50 states |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Compounded GLP-1 in oral-tablet and injection with named prescribers. | LegitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo. |
| Desk Score | 65/100C | 88/100B+ |
The verdict
Desk pick — Semaglutide OnlineSemaglutide Online takes this head-to-head with the higher Desk Score, 88/100 (B+) against 65/100 (C) for OnlyRx. OnlyRx still holds its ground where its strengths line up with yours.
Choose OnlyRx if…
Compounded GLP-1 in oral-tablet and injection with named prescribers.
$179/mo (promo rate) sema · From $249/mo (lowest dose rung) tirz
Choose Semaglutide Online if…
LegitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo.
$199/mo sema · $299/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: OnlyRx · Semaglutide Online.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs OnlyRx
- CoreAge Rx vs Semaglutide Online
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- Semaglutide Online vs Shed
- OnlyRx vs Vaylen
- Semaglutide Online vs Vaylen
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.