Head-to-head comparison
OnlyRx vs Vaylen
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
OnlyRx is a cash-pay GLP-1 telehealth platform offering compounded semaglutide and tirzepatide in both injection and oral disintegrating tablet (ODT) forms — an uncommon needle-free option.
$179/mo (promo rate) sema · From $249/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Promo pricing ($179 semaglutide injection) is prominent, but post-promo maintenance pricing isn't shown
Desk Score
The strongest all-rounder among the newer entrants — low pricing, brand access, oral routes, and all 50 states on one account.
$179/mo sema · $239/mo tirz
Marked down on: Newer operator with a shorter track record
Vaylen takes this head-to-head with the higher Desk Score, 90/100 (A−) against 65/100 (C) for OnlyRx. OnlyRx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
OnlyRx
65/100
C
Vaylen
90/100
A−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | OnlyRx | Vaylen |
|---|---|---|
| Semaglutide | $179/mopromo rate$179/mo (starting dose, promotional rate, compounded) | $179/mo$179/mo |
| Tirzepatide | From $249/molowest dose rung$249/mo (starting dose, compounded) | $239/mo$239/mo |
| Coverage | Not listed on OnlyRx's site (checked July 2026) | All 50 states |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Compounded GLP-1 in oral-tablet and injection with named prescribers. | People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach. |
| Desk Score | 65/100C | 90/100A− |
The verdict
Desk pick — VaylenVaylen takes this head-to-head with the higher Desk Score, 90/100 (A−) against 65/100 (C) for OnlyRx. OnlyRx still holds its ground where its strengths line up with yours.
Choose OnlyRx if…
Compounded GLP-1 in oral-tablet and injection with named prescribers.
$179/mo (promo rate) sema · From $249/mo (lowest dose rung) tirz
Choose Vaylen if…
People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.
$179/mo sema · $239/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: OnlyRx · Vaylen.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs OnlyRx
- CoreAge Rx vs Vaylen
- OnlyRx vs Shed
- Ondra Health vs Vaylen
- OnlyRx vs Semaglutide Online
- Sesame Care vs Vaylen
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.