Certification: On third-party certification, the site doesn't say. Where it ships: 40 states + DC (the FAQ names them; AL, AR, GA, HI, LA, MS, MO, ND, SC and TN are not served), as published on the site. Last checked: August 2026, against Enhance MD's own pages. Published price: Enhance MD publishes a figure for semaglutide and tirzepatide — the qualifiers are in "What does Enhance MD cost?" below. What it sells: Compounded medication only, injectable route only. Licensing & trust: 84/100 on the scored dimension of that name — one of the six in our published methodology. Checks out as far as the figures go, with one caveat: every price Enhance MD publishes carries a condition, so the number on the site is not the monthly bill.

C+79/100

Desk Score

Ranked #40

Enhance MD

Q: What does Enhance MD cost?

Semaglutide: $249 every 4 weeks month-to-month (13 charges a year); $237/mo billed every 12 weeks, $224/mo billed every 24 weeks, $212/mo only on the 12-month prepay billed every 48 weeks. That figure is billed on a cadence that is not a calendar month — $249 per billing period, so it lands more than twelve times a year. Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for semaglutide — only flat month-to-month rates compete there. Tirzepatide: $329 every 4 weeks month-to-month (13 charges a year); $313/mo billed every 12 weeks, $296/mo billed every 24 weeks, $280/mo only on the 12-month prepay billed every 48 weeks. That figure is billed on a cadence that is not a calendar month — $329 per billing period, so it lands more than twelve times a year. Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for tirzepatide — only flat month-to-month rates compete there. All figures as published on Enhance MD's own site and read in August 2026. Prices change — confirm before you order.

The clearest tiered compounded pricing in the ranking — separate lines for sema, tirzepatide, a microdose tier, and a sema+tirz combo — with lab testing built in.

Desk Score 79/100 (C+) · Verified August 2026

Visit Enhance MD ↗Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way.

What we checked — August 2026: Enhance MD's own plan pages, pricing, FAQ and policy pages, all read on the same visit.

What you're buying

Enhance MD sells four separate compounded GLP-1 protocols rather than one product with dose options, and it names each for what is in it. Core is semaglutide. Advanced is tirzepatide, a dual GLP-1 and GIP agonist. Elite combines semaglutide and tirzepatide in one injection and is pitched at patients who have plateaued on either alone. Microdosing Tirzepatide is a capped 1 mg weekly dose aimed at tolerability rather than maximum weight loss. There is an NAD+ line beside them.

Every protocol includes the same wrapper: medication delivered every four weeks, ongoing provider care, metabolic lab testing every six months, the same price at every dose, and free shipping. Lab work built into the price is genuinely uncommon in this category and it is the strongest thing on the site. Enhance.MD LLC is an administrative platform; the medicine is practiced by clinicians employed by Enhance Wellness PC and iThriveMD PC. The company is registered at 16192 Coastal Highway in Lewes, Delaware.

What it costs (and how it's billed)

Enhance MD publishes a complete four-rung ladder on every product page, and it labels the billing cycle on each rung, which is more honest than most — and also where the trap is. Every plan bills in multiples of four weeks. In August 2026, Core semaglutide read: 12-month billed every 48 weeks at $212/mo, 6-month billed every 24 weeks at $224/mo, 3-month billed every 12 weeks at $237/mo, and 1-month billed every 4 weeks at $249/mo. Advanced tirzepatide ran $280, $296, $313 and $329 on the same four cycles.

Four weeks is not a month. Paying "monthly" here is thirteen charges a year, about $3,237 a year of Core semaglutide rather than the $2,988 that $249/mo implies, and about $4,277 a year on Advanced rather than $3,948. The twelve-month plan bills every 48 weeks, so it is not twelve months either. Enhance MD prints the cycle beside every price, so the information is all there — it just does not add up the way the labels suggest.

The other two protocols follow the same shape. Elite runs from $379 a month on the four-week cycle down to $322 a month on the 48-week prepay. Microdosing Tirzepatide has no one-month rung at all: $189 a month billed every 12 weeks, $179 a month every 24 weeks, or $169 a month every 48 weeks, with medication delivered every twelve weeks. Discount codes were live on every page, $100 off three-month-and-longer plans and $50 off one-month plans. If a clinician finds you ineligible during onboarding, Enhance MD refunds 100% of your initial payment.

Who can order

This has improved, and it is worth saying so. The FAQ now publishes the list: Enhance MD says it is licensed in all fifty states but is launching by product availability, and names the 40 states plus Washington, D.C. where you can order today — Alaska, Arizona, California, Colorado, Connecticut, Delaware, Florida, Iowa, Idaho, Illinois, Indiana, Kansas, Kentucky, Massachusetts, Maryland, Maine, Michigan, Minnesota, Montana, North Carolina, Nebraska, New Hampshire, New Jersey, New Mexico, Nevada, New York, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Dakota, Texas, Utah, Virginia, Vermont, Washington, Wisconsin, West Virginia and Wyoming.

Read that as a list of ten exclusions: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee. The FAQ tells you to contact customer service for the most current position, which is a sensible hedge on a list that is clearly moving.

How the intake works

Four steps, and the second one is the differentiator: medical intake, lab work, provider consultation, home delivery. Enhance MD builds blood work into the path rather than treating it as optional, and repeats it every six months inside the plan price. A free consultation can be booked before you commit to anything.

Support is a published phone line, 1-888-299-5088, with real hours — Monday to Friday 8:00 AM to 8:00 PM Eastern and weekends 9:00 AM to 5:00 PM Eastern — plus support@enhance.md. Weekend cover on a published number puts Enhance MD ahead of most of the field on this one measure.

What we'd want changed

Bill in months or stop calling it a month. Every rate on this site carries "/mo" while every charge lands on a four-week cycle, and the effect is a thirteenth payment a year that nobody signed up for. The fix is a sentence: state the annual total beside each plan.

The comparison table elsewhere on the site compounds it by printing the 48-week prepay figures under a column headed "Monthly Price" — that column is the one number on the site that is not a monthly price. We would also like the pharmacy named. Enhance MD is specific about its clinical entities and about federal Section 503A compounding, then leaves the dispensing pharmacy anonymous, and there is no brand-name or oral route at all if compounded injections do not suit you.

Bottom line

Enhance MD is the most itemized compounded menu we cover — four distinct protocols, a published ladder on each, labs built in and a real phone line with weekend hours — and it now publishes its states too. The month-to-month rates to compare are $249 and $329, and the honest way to read them is as thirteen charges a year rather than twelve. Take Microdosing at $189 a month if tolerability is the worry; take the 48-week prepay only if you already know the molecule agrees with you.

Best for a patient who wants a named protocol, lab testing inside the price and a support line that answers on Saturday, and who does not need brand-name or oral options. Compare on the four-week cycle, not on the label — thirteen charges a year is the real shape of every plan here.

Is Enhance MD legit?

Only what Enhance MD publishes and what we could check ourselves — nothing inferred. See the methodology.

Certification: On third-party certification, the site doesn't say.
Where it ships: 40 states + DC (the FAQ names them; AL, AR, GA, HI, LA, MS, MO, ND, SC and TN are not served), as published on the site.
Last checked: August 2026, against Enhance MD's own pages.
Published price: Enhance MD publishes a figure for semaglutide and tirzepatide — the qualifiers are in "What does Enhance MD cost?" below.
What it sells: Compounded medication only, injectable route only.
Licensing & trust: 84/100 on the scored dimension of that name — one of the six in our published methodology.

Checks out as far as the figures go, with one caveat: every price Enhance MD publishes carries a condition, so the number on the site is not the monthly bill.

What does Enhance MD cost?

Each figure exactly as Enhance MD publishes it, with the condition attached to it spelled out.

Semaglutide

$249 every 4 weeks month-to-month (13 charges a year); $237/mo billed every 12 weeks, $224/mo billed every 24 weeks, $212/mo only on the 12-month prepay billed every 48 weeks

That figure is billed on a cadence that is not a calendar month — $249 per billing period, so it lands more than twelve times a year.

Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for semaglutide — only flat month-to-month rates compete there.

Tirzepatide

$329 every 4 weeks month-to-month (13 charges a year); $313/mo billed every 12 weeks, $296/mo billed every 24 weeks, $280/mo only on the 12-month prepay billed every 48 weeks

That figure is billed on a cadence that is not a calendar month — $329 per billing period, so it lands more than twelve times a year.

Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for tirzepatide — only flat month-to-month rates compete there.

All figures as published on Enhance MD's own site and read in August 2026. Prices change — confirm before you order.

Semaglutide: $249 per 4 weeks
Tirzepatide: $329 per 4 weeks
Coverage: 40 states + DC (the FAQ names them; AL, AR, GA, HI, LA, MS, MO, ND, SC and TN are not served)
Brand-name: Compounded only
Verification: Prices as published on Enhance MD's site — verified august 2026. Each figure's full condition is in “What does Enhance MD cost?” below.

Weigh Enhance MD against the full ranked field on the best semaglutide providers ranking, or line it up against its closest alternatives. Or go one-on-one: Enhance MD vs CoreAge Rx. Because Enhance MD dispenses compounded medication, it’s worth understanding whether compounded GLP-1 is legit and safe.

Desk Score breakdown

Each of the six scored dimensions. See the methodology.

Price transparency82/100

State access66/100

Molecule range78/100

Onboarding speed82/100

Support responsiveness86/100

Licensing & trust84/100

What we like

Transparent tiered pricing, with the billing cycle printed on every rung, across four named protocols — the microdose runs $189/mo billed every 12 weeks down to $169/mo on the 48-week prepay, and the semaglutide-plus-tirzepatide combination $379/mo every 4 weeks down to $322/mo on the 48-week prepay
Dose-flat pricing that doesn't climb as you titrate up
Metabolic lab testing every 6 months plus ongoing provider support
Adjacent NAD+ and longevity offerings on the same platform

Where points come off

Compounded only — not FDA-approved
No brand-name access and no oral or sublingual route
Serves 40 states plus DC, not all 50 — Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee are absent from the FAQ's own list
Every plan bills in multiples of 4 weeks, so paying "monthly" is 13 charges a year — about $3,237 a year on semaglutide rather than the $2,988 that $249/mo implies
The dispensing pharmacy is never named
Higher entry price than the budget compounders

The bottom line — C+

Best for: Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.

Enhance MD ranks #40 of 533 providers scored — see #1, CoreAge Rx here.

Visit Enhance MD ↗

Pricing and verification reflect Enhance MD's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on Enhance MD's site. Not medical advice; see our disclosure.

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