Head-to-head comparison
CoreAge Rx vs Enhance MD
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
$99/mo (12-month prepay) sema · $149/mo (12-month prepay) tirz · Verified August 2026
Marked down on: The advertised $99/$149 per month is a 12-month plan paid in full ($1,188 / $1,788 up front); no month-to-month price is published
Desk Score
The clearest tiered compounded pricing in the ranking — separate lines for sema, tirzepatide, a microdose tier, and a sema+tirz combo — with lab testing built in.
$249 per 4 weeks sema · $329 per 4 weeks tirz · Verified August 2026
Marked down on: Compounded only — not FDA-approved
CoreAge Rx takes this head-to-head with the higher Desk Score, 94/100 (A) against 79/100 (C+) for Enhance MD. Enhance MD still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
CoreAge Rx
94/100
A
Enhance MD
79/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | CoreAge Rx | Enhance MD |
|---|---|---|
| Semaglutide | $99/mo12-month prepay$99/mo only as a 12-month plan paid in full ($1,188 in one charge); the lander says "starting at, based on a 12-month plan paid in full"; no month-to-month price is published; same price at every dose; compounded injectable | $249 per 4 weeks$249 every 4 weeks month-to-month (13 charges a year); $237/mo billed every 12 weeks, $224/mo billed every 24 weeks, $212/mo only on the 12-month prepay billed every 48 weeks |
| Tirzepatide | $149/mo12-month prepay$149/mo only as a 12-month plan paid in full ($1,788 in one charge); no month-to-month price is published; same price at every dose; compounded injectable | $329 per 4 weeks$329 every 4 weeks month-to-month (13 charges a year); $313/mo billed every 12 weeks, $296/mo billed every 24 weeks, $280/mo only on the 12-month prepay billed every 48 weeks |
| Coverage | All 50 states | 40 states + DC (the FAQ names them; AL, AR, GA, HI, LA, MS, MO, ND, SC and TN are not served) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who can prepay a year and wants one dose-independent price with full nationwide reach. | Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes. |
| Desk Score | 94/100A | 79/100C+ |
The verdict
Desk pick — CoreAge RxCoreAge Rx takes this head-to-head with the higher Desk Score, 94/100 (A) against 79/100 (C+) for Enhance MD. Enhance MD still holds its ground where its strengths line up with yours.
Choose CoreAge Rx if…
Anyone who can prepay a year and wants one dose-independent price with full nationwide reach.
$99/mo (12-month prepay) sema · $149/mo (12-month prepay) tirz · All 50 states
Choose Enhance MD if…
Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.
$249 per 4 weeks sema · $329 per 4 weeks tirz · 40 states + DC (the FAQ names them; AL, AR, GA, HI, LA, MS, MO, ND, SC and TN are not served)
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: CoreAge Rx · Enhance MD.
More head-to-heads
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- CoreAge Rx vs Ondra Health
- EdgeRx vs Enhance MD
- CoreAge Rx vs Sesame Care
- Enhance MD vs Independent Wellness
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.