C71/100

Desk Score

Ranked #161

Cost Plus Drugs

Q: Is Cost Plus Drugs legit?

Certification: On third-party certification, the site doesn't say. Where it ships: All 50 states, as published on the site. Last checked: July 2026, against Cost Plus Drugs's own pages. Published price: Cost Plus Drugs publishes a figure for semaglutide — the qualifiers are in "What does Cost Plus Drugs cost?" below. What it sells: Brand-name medication as well as compounded, injectable route only. Licensing & trust: 75/100 on the scored dimension of that name — one of the six in our published methodology. Checks out as far as the figures go, with one caveat: every price Cost Plus Drugs publishes carries a condition, so the number on the site is not the monthly bill.

Q: What does Cost Plus Drugs cost?

Semaglutide: $279/mo (brand Ozempic). That is the FDA-approved brand product at $279 a month, which is a different medicine from compounded semaglutide at a different price. Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for semaglutide — only flat month-to-month rates compete there. Tirzepatide: Not listed on Cost Plus Drugs's site (checked July 2026). All figures as published on Cost Plus Drugs's own site and read in July 2026. Prices change — confirm before you order.

Mark Cuban's transparent-pricing online pharmacy.

Desk Score 71/100 (C) · Verified July 2026

Visit Cost Plus Drugs ↗Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way.

Is Cost Plus Drugs legit?

Only what Cost Plus Drugs publishes and what we could check ourselves — nothing inferred. See the methodology.

Certification: On third-party certification, the site doesn't say.
Where it ships: All 50 states, as published on the site.
Last checked: July 2026, against Cost Plus Drugs's own pages.
Published price: Cost Plus Drugs publishes a figure for semaglutide — the qualifiers are in "What does Cost Plus Drugs cost?" below.
What it sells: Brand-name medication as well as compounded, injectable route only.
Licensing & trust: 75/100 on the scored dimension of that name — one of the six in our published methodology.

Checks out as far as the figures go, with one caveat: every price Cost Plus Drugs publishes carries a condition, so the number on the site is not the monthly bill.

What does Cost Plus Drugs cost?

Each figure exactly as Cost Plus Drugs publishes it, with the condition attached to it spelled out.

Semaglutide

$279/mo (brand Ozempic)

That is the FDA-approved brand product at $279 a month, which is a different medicine from compounded semaglutide at a different price.

Because that figure carries a condition, it is held out of our "cheapest" rankings and out of the median we compute for semaglutide — only flat month-to-month rates compete there.

Tirzepatide

Not listed on Cost Plus Drugs's site (checked July 2026)

All figures as published on Cost Plus Drugs's own site and read in July 2026. Prices change — confirm before you order.

Semaglutide: $279/mobrand-name
Tirzepatide: Not listed on Cost Plus Drugs's site (checked July 2026)
Coverage: All 50 states
Brand-name: Yes
Verification: Prices as published on Cost Plus Drugs's site — verified july 2026. Each figure's full condition is in “What does Cost Plus Drugs cost?” below.

Line Cost Plus Drugs up against its closest alternatives. Or go one-on-one: Cost Plus Drugs vs CoreAge Rx.

Desk Score breakdown

Each of the six scored dimensions. See the methodology.

Price transparency62/100

State access86/100

Molecule range66/100

Onboarding speed76/100

Support responsiveness63/100

Licensing & trust75/100

What we like

Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
Around $279/mo for branded Ozempic — well below typical retail list prices
Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Where points come off

Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
Wegovy availability has been spotty — check current stock before assuming it ships
No compounded semaglutide or tirzepatide — brand only
No clinical follow-up — side-effect monitoring falls to your prescribing clinician

The bottom line — C

Best for: The cheapest transparent-pricing brand-name Ozempic channel.

Cost Plus Drugs ranks #161 of 542 providers scored — see #1, CoreAge Rx here.

Visit Cost Plus Drugs ↗

Pricing and verification reflect Cost Plus Drugs's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on Cost Plus Drugs's site. Not medical advice; see our disclosure.

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