Head-to-head comparison
Ondra Health vs PlexusDx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Compounded semaglutide from $149 a month and tirzepatide from $219 month-to-month, one price at every dose, with every dispensing pharmacy named on the site.
$149/mo sema · $219/mo tirz · Verified August 2026
Marked down on: Injectable only — no oral route
Desk Score
PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
From $149/mo (lowest dose rung) sema · From $249/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Compounded medications only; no FDA-approved brand options
Ondra Health takes this head-to-head with the higher Desk Score, 91/100 (A−) against 75/100 (C) for PlexusDx. PlexusDx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Ondra Health
91/100
A−
PlexusDx
75/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Ondra Health | PlexusDx |
|---|---|---|
| Semaglutide | $149/mo$149/mo month-to-month; $113/mo billed quarterly ($339); $108/mo on a 6-month plan ($649 up front); $96/mo on a 12-month plan ($1,149 up front); same price at every dose; compounded injectable | From $149/molowest dose rung$149/mo (starting dose, compounded) |
| Tirzepatide | $219/mo$219/mo month-to-month; $183/mo billed quarterly ($549); $167/mo on a 6-month plan ($999 up front); $142/mo on a 12-month plan ($1,699 up front); same price at every dose; compounded injectable | From $249/molowest dose rung$249/mo (starting dose, compounded) |
| Coverage | All 50 states and Puerto Rico | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who wants to know which pharmacy fills the vial before they pay, and is fine with a weekly injection. | Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization. |
| Desk Score | 91/100A− | 75/100C |
The verdict
Desk pick — Ondra HealthOndra Health takes this head-to-head with the higher Desk Score, 91/100 (A−) against 75/100 (C) for PlexusDx. PlexusDx still holds its ground where its strengths line up with yours.
Choose Ondra Health if…
Anyone who wants to know which pharmacy fills the vial before they pay, and is fine with a weekly injection.
$149/mo sema · $219/mo tirz · All 50 states and Puerto Rico
Choose PlexusDx if…
Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization.
From $149/mo (lowest dose rung) sema · From $249/mo (lowest dose rung) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Ondra Health · PlexusDx.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Ondra Health
- CoreAge Rx vs PlexusDx
- Ondra Health vs Sesame Care
- PlexusDx vs Tyde Wellness
- Ondra Health vs Vaylen
- PlexusDx vs Trellis Vitality
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.