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Head-to-head dispatch

Spry vs yourEra

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #306
Spry

Spry is a weight-loss and anti-aging telehealth platform pairing compounded semaglutide ($199/mo) and tirzepatide ($299/mo) with three longevity peptides — BPC-157, NAD+, and sermorelin ($249–$299/mo).

Marked down on: Displays an "FDA Approved" badge though compounded GLP-1s are not FDA-approved finished drugs — potentially misleading

vs
Dispatch #22Desk pick
yourEra

A rare compounded desk that publishes its pricing outright — both molecules plus a NAD+ and microdosing menu, across all 50 states.

Marked down on: Compounded only — not FDA-approved and not equivalent to brand Wegovy/Ozempic or Zepbound; availability can tighten as brand shortages resolve

yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 61/100 (C) for Spry. Spry still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Spry

61/100

C

Overall

yourEra

84/100

B

Price transparency

78
90

State access

24
92

Molecule range

66
84

Onboarding speed

75
80

Support responsiveness

66
80

Licensing & trust

59
78

The spec sheet

FieldSpryyourEra
Semaglutide$199/mo (starting dose, compounded)$199/mo
Tirzepatide$299/mo (starting dose, compounded)$299/mo
CoverageCoverage not publishedAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forReaders who want compounded GLP-1 plus anti-aging peptides under one membership.Patients who want transparent, upfront pricing on both semaglutide and tirzepatide and value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.
Desk Score61/100C84/100B

The verdict

Desk pick — yourEra

yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 61/100 (C) for Spry. Spry still holds its ground where its strengths line up with yours.

Choose Spry if…

Readers who want compounded GLP-1 plus anti-aging peptides under one membership.

$199/mo (starting dose, compounded) sema · $299/mo (starting dose, compounded) tirz · Coverage not published

Choose yourEra if…

Patients who want transparent, upfront pricing on both semaglutide and tirzepatide and value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.

$199/mo sema · $299/mo tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Spry · yourEra.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.