Head-to-head comparison
Sesame Care vs Wholesome Clinic
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
$149/mo (brand-name) sema · $299/mo (brand-name) tirz · Verified August 2026
Marked down on: A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
Desk Score
Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states.
From $149/mo (lowest dose rung) sema · From $349/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: $149 initial evaluation and $75 follow-up visits are billed separately from medication
Sesame Care takes this head-to-head with the higher Desk Score, 88/100 (B+) against 68/100 (C) for Wholesome Clinic. Wholesome Clinic still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Sesame Care
88/100
B+
Wholesome Clinic
68/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Sesame Care | Wholesome Clinic |
|---|---|---|
| Semaglutide | $149/mobrand-nameBrand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg; brand Wegovy and Ozempic injections $199/mo for the first two months at the lowest strengths, then $349/mo — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) | From $149/molowest dose rung$149/mo (starting dose, compounded) |
| Tirzepatide | $299/mobrand-nameBrand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg); the weight-loss program page prints a THIRD ladder for the same drug at $299 / $398 / $499 / $698 — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days | From $349/molowest dose rung$349/mo (starting dose, compounded) |
| Coverage | Nationwide marketplace | 7 states |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. | Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry. |
| Desk Score | 88/100B+ | 68/100C |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 88/100 (B+) against 68/100 (C) for Wholesome Clinic. Wholesome Clinic still holds its ground where its strengths line up with yours.
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
$149/mo (brand-name) sema · $299/mo (brand-name) tirz · Nationwide marketplace
Choose Wholesome Clinic if…
Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.
From $149/mo (lowest dose rung) sema · From $349/mo (lowest dose rung) tirz · 7 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Sesame Care · Wholesome Clinic.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.