Head-to-head comparison
Vaylen vs Wholesome Clinic
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
The strongest all-rounder among the newer entrants — low pricing, brand access, oral routes, and all 50 states on one account.
$179/mo sema · $239/mo tirz
Marked down on: Newer operator with a shorter track record
Desk Score
Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states.
From $149/mo (lowest dose rung) sema · From $349/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: $149 initial evaluation and $75 follow-up visits are billed separately from medication
Vaylen takes this head-to-head with the higher Desk Score, 90/100 (A−) against 68/100 (C) for Wholesome Clinic. Wholesome Clinic still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Vaylen
90/100
A−
Wholesome Clinic
68/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Vaylen | Wholesome Clinic |
|---|---|---|
| Semaglutide | $179/mo$179/mo | From $149/molowest dose rung$149/mo (starting dose, compounded) |
| Tirzepatide | $239/mo$239/mo | From $349/molowest dose rung$349/mo (starting dose, compounded) |
| Coverage | All 50 states | 7 states |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach. | Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry. |
| Desk Score | 90/100A− | 68/100C |
The verdict
Desk pick — VaylenVaylen takes this head-to-head with the higher Desk Score, 90/100 (A−) against 68/100 (C) for Wholesome Clinic. Wholesome Clinic still holds its ground where its strengths line up with yours.
Choose Vaylen if…
People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.
$179/mo sema · $239/mo tirz · All 50 states
Choose Wholesome Clinic if…
Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.
From $149/mo (lowest dose rung) sema · From $349/mo (lowest dose rung) tirz · 7 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Vaylen · Wholesome Clinic.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.