Head-to-head dispatch
Sesame Care vs System Labs
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Marked down on: A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
Desk Score
One molecule, one route, one price — a flat $179/mo tirzepatide subscription with the rate written out in the provider's own words rather than teased as a floor.
Marked down on: One molecule only — the program is a compounded tirzepatide-based GLP-1/GIP and there is no semaglutide product at all, so switching molecules means switching provider
Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 75/100 (C) for System Labs. System Labs still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Sesame Care
87/100
B+
System Labs
75/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Sesame Care | System Labs |
|---|---|---|
| Semaglutide | From $149/mo (brand Wegovy pill) | Not offered — no semaglutide product |
| Tirzepatide | Brand Zepbound (price varies) | $179/mo standing (compounded, all doses) |
| Coverage | Nationwide marketplace | Not disclosed |
| Brand-name | Yes | Compounded only |
| Oral option | Yes | Injectable only |
| Best for | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. | Readers who only want tirzepatide, want the monthly number settled before they start, and will not miss a semaglutide, oral or brand-name option. |
| Desk Score | 87/100B+ | 75/100C |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 75/100 (C) for System Labs. System Labs still holds its ground where its strengths line up with yours.
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace
Choose System Labs if…
Readers who only want tirzepatide, want the monthly number settled before they start, and will not miss a semaglutide, oral or brand-name option.
Not offered — no semaglutide product sema · $179/mo standing (compounded, all doses) tirz · Not disclosed
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Sesame Care · System Labs.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Sesame Care vs CoreAge Rx
- System Labs vs Vaylen
- Sesame Care vs Strut Health
- System Labs vs Ondra Health
- Sesame Care vs Invigor Medical
- System Labs vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.