Head-to-head comparison
Ondra Health vs System Labs
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Compounded semaglutide from $149 a month and tirzepatide from $219 month-to-month, one price at every dose, with every dispensing pharmacy named on the site.
$149/mo sema · $219/mo tirz · Verified August 2026
Marked down on: Injectable only — no oral route
Desk Score
One molecule, one route, one price — a flat $179/mo tirzepatide subscription with the rate written out in the provider's own words rather than teased as a floor.
Not offered — no semaglutide product sema · $179/mo tirz · Verified August 2026
Marked down on: One molecule only — the program is a compounded tirzepatide-based GLP-1/GIP and there is no semaglutide product at all, so switching molecules means switching provider
Ondra Health takes this head-to-head with the higher Desk Score, 91/100 (A−) against 75/100 (C) for System Labs. System Labs still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Ondra Health
91/100
A−
System Labs
75/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Ondra Health | System Labs |
|---|---|---|
| Semaglutide | $149/mo$149/mo month-to-month; $113/mo billed quarterly ($339); $108/mo on a 6-month plan ($649 up front); $96/mo on a 12-month plan ($1,149 up front); same price at every dose; compounded injectable | Not offered — no semaglutide productNot offered — no semaglutide product |
| Tirzepatide | $219/mo$219/mo month-to-month; $183/mo billed quarterly ($549); $167/mo on a 6-month plan ($999 up front); $142/mo on a 12-month plan ($1,699 up front); same price at every dose; compounded injectable | $179/mo$179/mo standing (compounded, all doses) |
| Coverage | All 50 states and Puerto Rico | Not listed on System Labs's site (checked August 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who wants to know which pharmacy fills the vial before they pay, and is fine with a weekly injection. | Readers who only want tirzepatide, want the monthly number settled before they start, and will not miss a semaglutide, oral or brand-name option. |
| Desk Score | 91/100A− | 75/100C |
The verdict
Desk pick — Ondra HealthOndra Health takes this head-to-head with the higher Desk Score, 91/100 (A−) against 75/100 (C) for System Labs. System Labs still holds its ground where its strengths line up with yours.
Choose Ondra Health if…
Anyone who wants to know which pharmacy fills the vial before they pay, and is fine with a weekly injection.
$149/mo sema · $219/mo tirz · All 50 states and Puerto Rico
Choose System Labs if…
Readers who only want tirzepatide, want the monthly number settled before they start, and will not miss a semaglutide, oral or brand-name option.
Not offered — no semaglutide product sema · $179/mo tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Ondra Health · System Labs.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Ondra Health
- CoreAge Rx vs System Labs
- Ondra Health vs Sesame Care
- System Labs vs Trimi
- Ondra Health vs Vaylen
- System Labs vs Tyde Wellness
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.