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Head-to-head dispatch

Rylo Health vs Tyde Wellness

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #96
Rylo Health

Texas-prescriber telehealth selling compounded semaglutide and tirzepatide alongside a peptide line, naming both its medical group and its dispensing pharmacy.

vs
Dispatch #8Desk pick
Tyde Wellness

Low entry pricing, oral options, and 50-state reach — a strong value pick for first-time GLP-1 patients.

Tyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 76/100 (C) for Rylo Health. Rylo Health still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Rylo Health

76/100

C

Overall

Tyde Wellness

89/100

B+

Price transparency

68
92

State access

86
96

Molecule range

72
92

Onboarding speed

82
85

Support responsiveness

79
83

Licensing & trust

75
88

The spec sheet

FieldRylo HealthTyde Wellness
Semaglutide$149/mo (promotional rate, compounded)$149/mo
Tirzepatide$249/mo (compounded)$249/mo
CoverageAll 50 statesAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyYes
Best forShoppers who want the pharmacy and medical group named before they buy.First-timers who want an affordable, needle-optional on-ramp available anywhere in the country.
Desk Score76/100C89/100B+

The verdict

Desk pick — Tyde Wellness

Tyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 76/100 (C) for Rylo Health. Rylo Health still holds its ground where its strengths line up with yours.

Choose Rylo Health if…

Shoppers who want the pharmacy and medical group named before they buy.

$149/mo (promotional rate, compounded) sema · $249/mo (compounded) tirz · All 50 states

Choose Tyde Wellness if…

First-timers who want an affordable, needle-optional on-ramp available anywhere in the country.

$149/mo sema · $249/mo tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Rylo Health · Tyde Wellness.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.