Head-to-head comparison
Ondra Health vs Rylo Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Compounded semaglutide from $149 a month and tirzepatide from $219 month-to-month, one price at every dose, with every dispensing pharmacy named on the site.
$149/mo sema · $219/mo tirz · Verified August 2026
Marked down on: Injectable only — no oral route
Desk Score
Texas-prescriber telehealth selling compounded semaglutide and tirzepatide alongside a peptide line, naming both its medical group and its dispensing pharmacy.
$149/mo (promo rate) sema · $249/mo tirz · Verified July 2026
Marked down on: Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
Ondra Health takes this head-to-head with the higher Desk Score, 91/100 (A−) against 76/100 (C) for Rylo Health. Rylo Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Ondra Health
91/100
A−
Rylo Health
76/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Ondra Health | Rylo Health |
|---|---|---|
| Semaglutide | $149/mo$149/mo month-to-month; $113/mo billed quarterly ($339); $108/mo on a 6-month plan ($649 up front); $96/mo on a 12-month plan ($1,149 up front); same price at every dose; compounded injectable | $149/mopromo rate$149/mo (promotional rate, compounded) |
| Tirzepatide | $219/mo$219/mo month-to-month; $183/mo billed quarterly ($549); $167/mo on a 6-month plan ($999 up front); $142/mo on a 12-month plan ($1,699 up front); same price at every dose; compounded injectable | $249/mo$249/mo (compounded) |
| Coverage | All 50 states and Puerto Rico | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who wants to know which pharmacy fills the vial before they pay, and is fine with a weekly injection. | Shoppers who want the pharmacy and medical group named before they buy. |
| Desk Score | 91/100A− | 76/100C |
The verdict
Desk pick — Ondra HealthOndra Health takes this head-to-head with the higher Desk Score, 91/100 (A−) against 76/100 (C) for Rylo Health. Rylo Health still holds its ground where its strengths line up with yours.
Choose Ondra Health if…
Anyone who wants to know which pharmacy fills the vial before they pay, and is fine with a weekly injection.
$149/mo sema · $219/mo tirz · All 50 states and Puerto Rico
Choose Rylo Health if…
Shoppers who want the pharmacy and medical group named before they buy.
$149/mo (promo rate) sema · $249/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Ondra Health · Rylo Health.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Ondra Health
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- Ondra Health vs Vaylen
- Rylo Health vs Trellis Vitality
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.