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Head-to-head dispatch

RxPepsDirect vs yourEra

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #351
RxPepsDirect

RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform whose advertised vial prices are not the whole cost.

$79/mo (starting dose, visit fee and shipping included, compounded) sema · $99/mo (starting dose, visit fee and shipping included, compounded) tirz · Verified August 1, 2026

Marked down on: The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once

vs
Dispatch #23Desk pick
yourEra

A compounded desk that advertises low floors — semaglutide from $79/mo, tirzepatide from $159/mo — with the plan price behind its intake, plus a NAD+ and microdosing menu, across all 50 states.

From $79/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) sema · From $159/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) tirz · Verified August 28, 2026

Marked down on: Compounded only — not FDA-approved and not equivalent to brand Wegovy/Ozempic or Zepbound; availability can tighten as brand shortages resolve

yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 57/100 (C) for RxPepsDirect. RxPepsDirect still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

RxPepsDirect

57/100

C

Overall

yourEra

84/100

B

Price transparency

30
90

State access

52
92

Molecule range

72
84

Onboarding speed

77
80

Support responsiveness

67
80

Licensing & trust

64
78

The spec sheet

FieldRxPepsDirectyourEra
Semaglutide$79/mo (starting dose, visit fee and shipping included, compounded)From $79/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded)
Tirzepatide$99/mo (starting dose, visit fee and shipping included, compounded)From $159/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded)
Coverage28 statesAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forThe all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.Patients drawn by a low advertised floor on both semaglutide and tirzepatide who are willing to complete the intake to learn the plan price, value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.
Desk Score57/100C84/100B

The verdict

Desk pick — yourEra

yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 57/100 (C) for RxPepsDirect. RxPepsDirect still holds its ground where its strengths line up with yours.

Choose RxPepsDirect if…

The all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.

$79/mo (starting dose, visit fee and shipping included, compounded) sema · $99/mo (starting dose, visit fee and shipping included, compounded) tirz · 28 states

Choose yourEra if…

Patients drawn by a low advertised floor on both semaglutide and tirzepatide who are willing to complete the intake to learn the plan price, value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.

From $79/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) sema · From $159/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: RxPepsDirect · yourEra.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.