Head-to-head comparison
Lean Meds vs RxPepsDirect
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Lean Meds publishes its whole price ladder in the open — both molecules, every plan length — and names the four pharmacies that dispense it, which most sellers in this category never do.
$79/mo sema · $109/mo tirz · Verified September 2026
Marked down on: The advertised $49 is the twelve-month tier rather than the month-to-month rate of $79, and tirzepatide runs the same gap between $95 and $109.
Desk Score
RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform whose advertised vial prices are not the whole cost.
From $79/mo (lowest dose rung) sema · From $99/mo (lowest dose rung) tirz · Verified August 2026
Marked down on: The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
Lean Meds takes this head-to-head with the higher Desk Score, 83/100 (B) against 66/100 (C) for RxPepsDirect. RxPepsDirect still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Lean Meds
83/100
B
RxPepsDirect
66/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Lean Meds | RxPepsDirect |
|---|---|---|
| Semaglutide | $79/mo$79/mo | From $79/molowest dose rung$79/mo (starting dose, visit fee and shipping included, compounded) |
| Tirzepatide | $109/mo$109/mo | From $99/molowest dose rung$99/mo (starting dose, visit fee and shipping included, compounded) |
| Coverage | All 50 states | 28 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who wants to see the full price and the dispensing pharmacy before starting a questionnaire. | The all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states. |
| Desk Score | 83/100B | 66/100C |
The verdict
Desk pick — Lean MedsLean Meds takes this head-to-head with the higher Desk Score, 83/100 (B) against 66/100 (C) for RxPepsDirect. RxPepsDirect still holds its ground where its strengths line up with yours.
Choose Lean Meds if…
Anyone who wants to see the full price and the dispensing pharmacy before starting a questionnaire.
$79/mo sema · $109/mo tirz · All 50 states
Choose RxPepsDirect if…
The all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.
From $79/mo (lowest dose rung) sema · From $99/mo (lowest dose rung) tirz · 28 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Lean Meds · RxPepsDirect.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Lean Meds
- CoreAge Rx vs RxPepsDirect
- Lean Meds vs yourEra
- RxPepsDirect vs yourEra
- Lean Meds vs Sunlight
- RxPepsDirect vs Sunlight
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.