Head-to-head comparison
PCOS Sisters vs Wholesome Clinic
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.
$150/mo (+ membership fee) sema · $150/mo (+ membership fee) tirz · Verified July 2026
Marked down on: Only 12 states served
Desk Score
Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states.
From $149/mo (lowest dose rung) sema · From $349/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: $149 initial evaluation and $75 follow-up visits are billed separately from medication
PCOS Sisters takes this head-to-head with the higher Desk Score, 71/100 (C) against 68/100 (C) for Wholesome Clinic. Wholesome Clinic still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
PCOS Sisters
71/100
C
Wholesome Clinic
68/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | PCOS Sisters | Wholesome Clinic |
|---|---|---|
| Semaglutide | $150/mo+ membership fee$150/mo (plus a separate fee, compounded) | From $149/molowest dose rung$149/mo (starting dose, compounded) |
| Tirzepatide | $150/mo+ membership fee$150/mo (plus a separate fee, compounded) | From $349/molowest dose rung$349/mo (starting dose, compounded) |
| Coverage | 12 states | 7 states |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Women with pcos seeking glp-1 weight and metabolic care. | Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry. |
| Desk Score | 71/100C | 68/100C |
The verdict
Desk pick — PCOS SistersPCOS Sisters takes this head-to-head with the higher Desk Score, 71/100 (C) against 68/100 (C) for Wholesome Clinic. Wholesome Clinic still holds its ground where its strengths line up with yours.
Choose PCOS Sisters if…
Women with pcos seeking glp-1 weight and metabolic care.
$150/mo (+ membership fee) sema · $150/mo (+ membership fee) tirz · 12 states
Choose Wholesome Clinic if…
Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.
From $149/mo (lowest dose rung) sema · From $349/mo (lowest dose rung) tirz · 7 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: PCOS Sisters · Wholesome Clinic.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs PCOS Sisters
- CoreAge Rx vs Wholesome Clinic
- PCOS Sisters vs Sesame Care
- Sesame Care vs Wholesome Clinic
- PCOS Sisters vs Vaylen
- Vaylen vs Wholesome Clinic
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.