Head-to-head dispatch
Open Water Rx vs Wisp
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site.
$249/mo (compounded) sema · $339/mo (compounded) tirz · Verified July 26, 2026
Marked down on: Limited public data — most details are gated behind signup or rendered only in JavaScript
Desk Score
Wisp (hellowisp.com) is a large women's telehealth service whose weight care aisle offers brand-name Wegovy, Zepbound and Saxenda written for your own pharmacy, plus compounded sublingual semaglutide drops at $225/month on top of a recurring $99/month consult.
$225/mo (compounded sublingual drops, 15 mL) plus the separate $99/mo Weight Care Consult — $324/mo all in sema · Verified August 29, 2026
Marked down on: The consult is a separate, recurring $99/month charge that the product card does not show, so the real cost of the sublingual program is $324/mo — well above a compounded injection at most sellers, for the weaker formulation
Wisp takes this head-to-head with the higher Desk Score, 79/100 (C+) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Open Water Rx
60/100
C
Wisp
79/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Open Water Rx | Wisp |
|---|---|---|
| Semaglutide | $249/mo (compounded) | $225/mo (compounded sublingual drops, 15 mL) plus the separate $99/mo Weight Care Consult — $324/mo all in |
| Tirzepatide | $339/mo (compounded) | Not listed on Wisp's site (checked August 29, 2026) |
| Coverage | Not listed on Open Water Rx's site (checked July 26, 2026) | 40 states plus DC for the branded injectables (12 of them delivery-only or local-pickup-only); 27 states plus DC for the compounded sublingual semaglutide |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Transparency listing only — verify against vetted providers first. | A woman who wants brand-name Wegovy or Zepbound written by an established clinic and filled on her own insurance — not for anyone shopping compounded injections on price. |
| Desk Score | 60/100C | 79/100C+ |
The verdict
Desk pick — WispWisp takes this head-to-head with the higher Desk Score, 79/100 (C+) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.
Choose Open Water Rx if…
Transparency listing only — verify against vetted providers first.
$249/mo (compounded) sema · $339/mo (compounded) tirz
Choose Wisp if…
A woman who wants brand-name Wegovy or Zepbound written by an established clinic and filled on her own insurance — not for anyone shopping compounded injections on price.
$225/mo (compounded sublingual drops, 15 mL) plus the separate $99/mo Weight Care Consult — $324/mo all in sema · 40 states plus DC for the branded injectables (12 of them delivery-only or local-pickup-only); 27 states plus DC for the compounded sublingual semaglutide
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Open Water Rx · Wisp.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Open Water Rx
- CoreAge Rx vs Wisp
- He & She MD vs Open Water Rx
- Invigor Medical vs Wisp
- NuDay Rx vs Open Water Rx
- RxSpan MD vs Wisp
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.