Head-to-head comparison
Onyx Weight Loss vs Peak Wellness
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.
From $228/mo (lowest dose rung) sema · From $280/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
Desk Score
All-inclusive injectable plans in every state at $249/mo for semaglutide and $349/mo for tirzepatide, flat at every dose — from a seller that names four compounding pharmacies and its provider group.
$249/mo sema · $349/mo tirz · Verified August 2026
Marked down on: The banner and the FAQ both advertise "just $179", which is a first month — the standing rate is $249/mo, and $70/mo more on either molecule from month two
Peak Wellness takes this head-to-head with the higher Desk Score, 81/100 (B−) against 62/100 (C) for Onyx Weight Loss. Onyx Weight Loss still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Onyx Weight Loss
62/100
C
Peak Wellness
81/100
B−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Onyx Weight Loss | Peak Wellness |
|---|---|---|
| Semaglutide | From $228/molowest dose rung$228/mo (starting dose, compounded) | $249/mo$249/mo month-to-month ($179 first month); $199/mo on the 3-month plan, $165/mo on the 6-month plan |
| Tirzepatide | From $280/molowest dose rung$280/mo (starting dose, compounded) | $349/mo$349/mo month-to-month ($279 first month); $279/mo on the 3-month plan ($837 up front), $232/mo on the 6-month plan ($1,397 up front) |
| Coverage | 8 states | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | NP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. | Patients who want an all-inclusive injection plan available in every state and care who compounds the vial, and who will budget the standing rate rather than the advertised first month. |
| Desk Score | 62/100C | 81/100B− |
The verdict
Desk pick — Peak WellnessPeak Wellness takes this head-to-head with the higher Desk Score, 81/100 (B−) against 62/100 (C) for Onyx Weight Loss. Onyx Weight Loss still holds its ground where its strengths line up with yours.
Choose Onyx Weight Loss if…
NP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.
From $228/mo (lowest dose rung) sema · From $280/mo (lowest dose rung) tirz · 8 states
Choose Peak Wellness if…
Patients who want an all-inclusive injection plan available in every state and care who compounds the vial, and who will budget the standing rate rather than the advertised first month.
$249/mo sema · $349/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Onyx Weight Loss · Peak Wellness.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.