Head-to-head dispatch
EdgeRx vs Onyx Weight Loss
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
A men's-only protocol shop with flat, disclosed GLP-1 pricing, a named Chief Medical Advisor, and a named 503A compounding pharmacy — rare transparency for this tier of the ranking.
Marked down on: Men-only — not built for or marketed to women or other readers
Desk Score
Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.
Marked down on: Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
EdgeRx takes this head-to-head with the higher Desk Score, 82/100 (B−) against 62/100 (C) for Onyx Weight Loss. Onyx Weight Loss still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
EdgeRx
82/100
B−
Onyx Weight Loss
62/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | EdgeRx | Onyx Weight Loss |
|---|---|---|
| Semaglutide | $229/mo injectable | $228/mo (starting dose, compounded) |
| Tirzepatide | $299/mo injectable | $280/mo (starting dose, compounded) |
| Coverage | 46 states (excludes Arkansas, Indiana, Minnesota, South Carolina) | 8 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Men who want a straightforward, disclosed weekly-injectable price on either molecule and value knowing the pharmacy by name. | Readers who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. |
| Desk Score | 82/100B− | 62/100C |
The verdict
Desk pick — EdgeRxEdgeRx takes this head-to-head with the higher Desk Score, 82/100 (B−) against 62/100 (C) for Onyx Weight Loss. Onyx Weight Loss still holds its ground where its strengths line up with yours.
Choose EdgeRx if…
Men who want a straightforward, disclosed weekly-injectable price on either molecule and value knowing the pharmacy by name.
$229/mo injectable sema · $299/mo injectable tirz · 46 states (excludes Arkansas, Indiana, Minnesota, South Carolina)
Choose Onyx Weight Loss if…
Readers who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.
$228/mo (starting dose, compounded) sema · $280/mo (starting dose, compounded) tirz · 8 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: EdgeRx · Onyx Weight Loss.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- EdgeRx vs CoreAge Rx
- Onyx Weight Loss vs Vaylen
- EdgeRx vs Strut Health
- Onyx Weight Loss vs Ondra Health
- EdgeRx vs Invigor Medical
- Onyx Weight Loss vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.