Head-to-head comparison
NuDay Rx vs Open Water Rx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support.
$249/mo sema · $329/mo tirz · Verified June 2026
Marked down on: Compounded semaglutide ($249) is pricier than some budget competitors
Desk Score
Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site.
$249/mo sema · $339/mo tirz · Verified July 2026
Marked down on: Limited public data — most details are gated behind signup or rendered only in JavaScript
NuDay Rx takes this head-to-head with the higher Desk Score, 71/100 (C) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
NuDay Rx
71/100
C
Open Water Rx
60/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | NuDay Rx | Open Water Rx |
|---|---|---|
| Semaglutide | $249/mo$249/mo (compounded) | $249/mo$249/mo (compounded) |
| Tirzepatide | $329/mo$329/mo (compounded) | $339/mo$339/mo (compounded) |
| Coverage | Not listed on NuDay Rx's site (checked June 2026) | Not listed on Open Water Rx's site (checked July 2026) |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult. | Transparency listing only — verify against vetted providers first. |
| Desk Score | 71/100C | 60/100C |
The verdict
Desk pick — NuDay RxNuDay Rx takes this head-to-head with the higher Desk Score, 71/100 (C) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.
Choose NuDay Rx if…
Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult.
$249/mo sema · $329/mo tirz
Choose Open Water Rx if…
Transparency listing only — verify against vetted providers first.
$249/mo sema · $339/mo tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: NuDay Rx · Open Water Rx.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs NuDay Rx
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- Open Water Rx vs RxSpan MD
- He & She MD vs NuDay Rx
- He & She MD vs Open Water Rx
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.