Head-to-head comparison
Luvo Health vs Open Water Rx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
A multi-program telehealth brand with a full per-4-week price list published for every GLP-1 molecule and route — compounded and brand-name Ozempic, injection and tablet — plus a separate NAD+/sermorelin longevity line, also available.
$249 per 4 weeks sema · $339 per 4 weeks tirz · Verified August 2026
Marked down on: Price varies significantly by molecule, route and term length — the 4-week rate runs meaningfully higher per week than the 12/24/52-week commitments, a real lock-in tradeoff to weigh before choosing a term
Desk Score
Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site.
$249/mo sema · $339/mo tirz · Verified July 2026
Marked down on: Limited public data — most details are gated behind signup or rendered only in JavaScript
Luvo Health takes this head-to-head with the higher Desk Score, 68/100 (C) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Luvo Health
68/100
C
Open Water Rx
60/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Luvo Health | Open Water Rx |
|---|---|---|
| Semaglutide | $249 per 4 weeks$249/4wk injection ($62/wk); $279/4wk tablets ($70/wk) — compounded, cheaper on longer terms | $249/mo$249/mo (compounded) |
| Tirzepatide | $339 per 4 weeks$339/4wk injection ($85/wk) — compounded, cheaper on longer terms | $339/mo$339/mo (compounded) |
| Coverage | Not listed on Luvo Health's site (checked August 2026) | Not listed on Open Water Rx's site (checked July 2026) |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Shoppers who want compounded and brand GLP-1s, an oral tablet option, and a published price list, and are willing to commit to a longer term to bring the weekly rate down. | Transparency listing only — verify against vetted providers first. |
| Desk Score | 68/100C | 60/100C |
The verdict
Desk pick — Luvo HealthLuvo Health takes this head-to-head with the higher Desk Score, 68/100 (C) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.
Choose Luvo Health if…
Shoppers who want compounded and brand GLP-1s, an oral tablet option, and a published price list, and are willing to commit to a longer term to bring the weekly rate down.
$249 per 4 weeks sema · $339 per 4 weeks tirz
Choose Open Water Rx if…
Transparency listing only — verify against vetted providers first.
$249/mo sema · $339/mo tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Luvo Health · Open Water Rx.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Luvo Health
- CoreAge Rx vs Open Water Rx
- Luvo Health vs RxSpan MD
- Open Water Rx vs RxSpan MD
- He & She MD vs Luvo Health
- He & She MD vs Open Water Rx
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.