Head-to-head dispatch
Enhance MD vs WeightRx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
The clearest tiered compounded pricing in the ranking — separate lines for sema, tirzepatide, a microdose tier, and a sema+tirz combo — with lab testing built in.
Marked down on: Compounded only — not FDA-approved
Desk Score
WeightRx is a telehealth provider publishing compounded semaglutide at $250/mo and compounded tirzepatide at $83/mo.
Marked down on: The $83 monthly rate is advertised as '$83/month ($997/year)', which is twelve months of it — no month-to-month rate is separately published, and the terms state that a rate is locked for its full term
Enhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 66/100 (C) for WeightRx. WeightRx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Enhance MD
85/100
B
WeightRx
66/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Enhance MD | WeightRx |
|---|---|---|
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $250/mo (compounded) |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $83/mo (term not published, compounded) |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes. | Readers who want the lowest published tirzepatide figure, if you are willing to complete intake before you can read the plan terms. |
| Desk Score | 85/100B | 66/100C |
The verdict
Desk pick — Enhance MDEnhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 66/100 (C) for WeightRx. WeightRx still holds its ground where its strengths line up with yours.
Choose Enhance MD if…
Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.
$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay sema · $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay tirz · Not publicly listed
Choose WeightRx if…
Readers who want the lowest published tirzepatide figure, if you are willing to complete intake before you can read the plan terms.
$250/mo (compounded) sema · $83/mo (term not published, compounded) tirz · Coverage not published
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Enhance MD · WeightRx.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Enhance MD vs CoreAge Rx
- WeightRx vs Vaylen
- Enhance MD vs Strut Health
- WeightRx vs Ondra Health
- Enhance MD vs Invigor Medical
- WeightRx vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.