Head-to-head dispatch
Enhance MD vs TRT Nation
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
The clearest tiered compounded pricing in the ranking — separate lines for sema, tirzepatide, a microdose tier, and a sema+tirz combo — with lab testing built in.
Marked down on: Compounded only — not FDA-approved
Desk Score
TRT Nation is a men's telehealth platform focused primarily on testosterone replacement therapy, with compounded GLP-1 weight loss as a secondary vertical.
Marked down on: Weight loss is secondary to core TRT business
Enhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 51/100 (C) for TRT Nation. TRT Nation still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Enhance MD
85/100
B
TRT Nation
51/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Enhance MD | TRT Nation |
|---|---|---|
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | Not disclosed |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $219/mo |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes. | Readers who want men wanting flat-rate compounded tirzepatide alongside a TRT-focused platform. |
| Desk Score | 85/100B | 51/100C |
The verdict
Desk pick — Enhance MDEnhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 51/100 (C) for TRT Nation. TRT Nation still holds its ground where its strengths line up with yours.
Choose Enhance MD if…
Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.
$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay sema · $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay tirz · Not publicly listed
Choose TRT Nation if…
Readers who want men wanting flat-rate compounded tirzepatide alongside a TRT-focused platform.
Not disclosed sema · $219/mo tirz · Coverage not published
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Enhance MD · TRT Nation.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Enhance MD vs CoreAge Rx
- TRT Nation vs Vaylen
- Enhance MD vs Strut Health
- TRT Nation vs Ondra Health
- Enhance MD vs Invigor Medical
- TRT Nation vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.