Head-to-head dispatch
Enhance MD vs Luma Meds
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
The clearest tiered compounded pricing in the ranking — separate lines for sema, tirzepatide, a microdose tier, and a sema+tirz combo — with lab testing built in.
Marked down on: Compounded only — not FDA-approved
Desk Score
Fully online compounded GLP-1 telehealth offering semaglutide and tirzepatide injections from FDA-regulated 503A and 503B compounding pharmacies.
Marked down on: Compounding pharmacy partner not publicly named
Enhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 64/100 (C) for Luma Meds. Luma Meds still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Enhance MD
85/100
B
Luma Meds
64/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Enhance MD | Luma Meds |
|---|---|---|
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $249/mo (compounded) |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $299/mo (compounded) |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes. | People who want a LegitScript-certified compounded GLP-1 plan with free shipping and provider support. |
| Desk Score | 85/100B | 64/100C |
The verdict
Desk pick — Enhance MDEnhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 64/100 (C) for Luma Meds. Luma Meds still holds its ground where its strengths line up with yours.
Choose Enhance MD if…
Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.
$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay sema · $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay tirz · Not publicly listed
Choose Luma Meds if…
People who want a LegitScript-certified compounded GLP-1 plan with free shipping and provider support.
$249/mo (compounded) sema · $299/mo (compounded) tirz · Coverage not published
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Enhance MD · Luma Meds.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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- Enhance MD vs Invigor Medical
- Luma Meds vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.