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Head-to-head dispatch

Curve vs Enhance MD

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #127
Curve

Curve (Try Curve LLC) is a telehealth platform selling compounded semaglutide and tirzepatide, prescribed by Beluga Health providers and dispensed by VialsRx — but its site would not load over HTTPS when we last looked.

Marked down on: Its HTTPS certificate configuration failed from a clean network on August 29, 2026 — the host offered no certificate on trycurve.co or on www.trycurve.co, though it still answered on port 80 — so a reader cannot open the site.

vs
Dispatch #18Desk pick
Enhance MD

The clearest tiered compounded pricing in the ranking — separate lines for sema, tirzepatide, a microdose tier, and a sema+tirz combo — with lab testing built in.

$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay sema · $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay tirz · Verified August 28, 2026

Marked down on: Compounded only — not FDA-approved

Enhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 72/100 (C) for Curve. Curve still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Curve

72/100

C

Overall

Enhance MD

85/100

B

Price transparency

52
82

State access

86
60

Molecule range

66
78

Onboarding speed

91
82

Support responsiveness

69
86

Licensing & trust

83
84

The spec sheet

FieldCurveEnhance MD
SemaglutideNot listed on Curve's site$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay
TirzepatideNot listed on Curve's site$329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay
CoverageAll 50 statesNot listed on Enhance MD's site (checked August 28, 2026)
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forCompounded semaglutide or tirzepatide with flat per-dose pricing from a LegitScript-certified seller, once the site is reachable again.Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.
Desk Score72/100C85/100B

The verdict

Desk pick — Enhance MD

Enhance MD takes this head-to-head with the higher Desk Score, 85/100 (B) against 72/100 (C) for Curve. Curve still holds its ground where its strengths line up with yours.

Choose Curve if…

Compounded semaglutide or tirzepatide with flat per-dose pricing from a LegitScript-certified seller, once the site is reachable again.

All 50 states

Choose Enhance MD if…

Patients who want fully itemized compounded options and ongoing metabolic oversight, and don't need brand-name or oral routes.

$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay sema · $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay tirz

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Curve · Enhance MD.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.