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Head-to-head dispatch

Cost Plus Drugs vs Fierce Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #124
Cost Plus Drugs

Mark Cuban's transparent-pricing online pharmacy.

Marked down on: Fulfillment only — no telehealth intake; you need a prescription from an outside clinician

vs
Dispatch #123Desk pick
Fierce Health

Fierce Health is a direct-to-consumer telehealth brand selling compounded semaglutide and tirzepatide in both standard and microdose programs, alongside a longevity catalog.

Marked down on: No named 503A compounding pharmacy partner — only generic 'partner pharmacies' language

Fierce Health takes this head-to-head with the higher Desk Score, 72/100 (C) against 71/100 (C) for Cost Plus Drugs. Cost Plus Drugs still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Cost Plus Drugs

71/100

C

Overall

Fierce Health

72/100

C

Price transparency

62
76

State access

86
66

Molecule range

66
79

Onboarding speed

76
70

Support responsiveness

63
68

Licensing & trust

75
66

The spec sheet

FieldCost Plus DrugsFierce Health
Semaglutide$279/mo (brand Ozempic)$297/mo (3-month plan, compounded)
TirzepatideNot disclosed$497/mo (3-month plan, compounded)
CoverageAll 50 states30 states
Brand-nameYesYes
Oral optionInjectable onlyInjectable only
Best forReaders who want the cheapest transparent-pricing brand-name Ozempic channel.Readers who want compounded GLP-1 with standard and microdose protocols plus a longevity catalog.
Desk Score71/100C72/100C

The verdict

Desk pick — Fierce Health

Fierce Health takes this head-to-head with the higher Desk Score, 72/100 (C) against 71/100 (C) for Cost Plus Drugs. Cost Plus Drugs still holds its ground where its strengths line up with yours.

Choose Cost Plus Drugs if…

Readers who want the cheapest transparent-pricing brand-name Ozempic channel.

$279/mo (brand Ozempic) sema · Not disclosed tirz · All 50 states

Choose Fierce Health if…

Readers who want compounded GLP-1 with standard and microdose protocols plus a longevity catalog.

$297/mo (3-month plan, compounded) sema · $497/mo (3-month plan, compounded) tirz · 30 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Cost Plus Drugs · Fierce Health.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.