Head-to-head comparison
Cost Plus Drugs vs Fierce Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Mark Cuban's transparent-pricing online pharmacy.
$279/mo (brand-name) sema · Verified July 2026
Marked down on: Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
Desk Score
Fierce Health is a direct-to-consumer telehealth brand selling compounded semaglutide and tirzepatide in both standard and microdose programs, alongside a longevity catalog.
$297/mo (3-month prepay) sema · $497/mo (3-month prepay) tirz · Verified July 2026
Marked down on: No named 503A compounding pharmacy partner — only generic 'partner pharmacies' language
Fierce Health takes this head-to-head with the higher Desk Score, 72/100 (C) against 71/100 (C) for Cost Plus Drugs. Cost Plus Drugs still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Cost Plus Drugs
71/100
C
Fierce Health
72/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Cost Plus Drugs | Fierce Health |
|---|---|---|
| Semaglutide | $279/mobrand-name$279/mo (brand Ozempic) | $297/mo3-month prepay$297/mo (3-month plan, compounded) |
| Tirzepatide | Not listed on Cost Plus Drugs's site (checked July 2026) | $497/mo3-month prepay$497/mo (3-month plan, compounded) |
| Coverage | All 50 states | 30 states |
| Brand-name | Yes | Yes |
| Oral option | Injectable only | Injectable only |
| Best for | The cheapest transparent-pricing brand-name Ozempic channel. | Compounded GLP-1 with standard and microdose protocols plus a longevity catalog. |
| Desk Score | 71/100C | 72/100C |
The verdict
Desk pick — Fierce HealthFierce Health takes this head-to-head with the higher Desk Score, 72/100 (C) against 71/100 (C) for Cost Plus Drugs. Cost Plus Drugs still holds its ground where its strengths line up with yours.
Choose Cost Plus Drugs if…
The cheapest transparent-pricing brand-name Ozempic channel.
$279/mo (brand-name) sema · All 50 states
Choose Fierce Health if…
Compounded GLP-1 with standard and microdose protocols plus a longevity catalog.
$297/mo (3-month prepay) sema · $497/mo (3-month prepay) tirz · 30 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Cost Plus Drugs · Fierce Health.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Cost Plus Drugs
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- AskRx vs Fierce Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.