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Head-to-head dispatch

CLYR Health vs Open Water Rx

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #166Desk pick
CLYR Health

CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments.

Marked down on: State availability gated behind intake; not published on the marketing site

vs
Dispatch #318
Open Water Rx

Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site.

Marked down on: Limited public data — most details are gated behind signup or rendered only in JavaScript

CLYR Health takes this head-to-head with the higher Desk Score, 68/100 (C) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

CLYR Health

68/100

C

Overall

Open Water Rx

60/100

C

Price transparency

76
86

State access

24
24

Molecule range

90
90

Onboarding speed

73
50

Support responsiveness

72
48

Licensing & trust

86
40

The spec sheet

FieldCLYR HealthOpen Water Rx
Semaglutide$229/mo (compounded)$249/mo (compounded)
Tirzepatide$249/mo (compounded)$339/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-nameYesYes
Oral optionYesYes
Best forReaders who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.Readers who want transparency listing only — verify against vetted providers first.
Desk Score68/100C60/100C

The verdict

Desk pick — CLYR Health

CLYR Health takes this head-to-head with the higher Desk Score, 68/100 (C) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.

Choose CLYR Health if…

Readers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.

$229/mo (compounded) sema · $249/mo (compounded) tirz · Coverage not published

Choose Open Water Rx if…

Readers who want transparency listing only — verify against vetted providers first.

$249/mo (compounded) sema · $339/mo (compounded) tirz · Coverage not published

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: CLYR Health · Open Water Rx.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.