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Head-to-head dispatch

Open Water Rx vs Vaylen

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #311
Open Water Rx

Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site.

vs
Dispatch #2Desk pick
Vaylen

The strongest all-rounder among the newer entrants — low pricing, brand access, oral routes, and all 50 states on one account.

Vaylen takes this head-to-head with the higher Desk Score, 91/100 (A−) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Open Water Rx

60/100

C

Overall

Vaylen

91/100

A−

Price transparency

86
88

State access

24
96

Molecule range

90
96

Onboarding speed

50
86

Support responsiveness

48
84

Licensing & trust

40
90

The spec sheet

FieldOpen Water RxVaylen
Semaglutide$249/mo (compounded)$179/mo
Tirzepatide$339/mo (compounded)$239/mo
CoverageCoverage not publishedAll 50 states
Brand-nameYesYes
Oral optionYesYes
Best forReaders who want transparency listing only — verify against vetted providers first.People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.
Desk Score60/100C91/100A−

The verdict

Desk pick — Vaylen

Vaylen takes this head-to-head with the higher Desk Score, 91/100 (A−) against 60/100 (C) for Open Water Rx. Open Water Rx still holds its ground where its strengths line up with yours.

Choose Open Water Rx if…

Readers who want transparency listing only — verify against vetted providers first.

$249/mo (compounded) sema · $339/mo (compounded) tirz · Coverage not published

Choose Vaylen if…

People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.

$179/mo sema · $239/mo tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Open Water Rx · Vaylen.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.