Head-to-head dispatch
Amazon One Medical vs Sprout Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products).
Marked down on: Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
Desk Score
A LegitScript-certified desk that pairs low-cost compounded semaglutide and tirzepatide with a real brand-name Wegovy and Zepbound path — and a near-frictionless, often visit-free start.
$299/mo sema · $349/mo tirz · Verified August 28, 2026
Marked down on: FDA issued Sprout Health Partners LLC dba Sprout Health a warning letter in September 2025; the letter is public in FDA's warning-letter database
FDAWarning letter issued to Sprout Health Partners LLC dba Sprout Health in September 2025. See the FDA warning-letter database.
Sprout Health takes this head-to-head with the higher Desk Score, 86/100 (B) against 80/100 (B−) for Amazon One Medical. Amazon One Medical still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Amazon One Medical
80/100
B−
Sprout Health
86/100
B
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Amazon One Medical | Sprout Health |
|---|---|---|
| Semaglutide | Not listed on Amazon One Medical's site (checked July 20, 2026) | $299/mo |
| Tirzepatide | Not listed on Amazon One Medical's site (checked July 20, 2026) | $349/mo |
| Coverage | All 50 states | Not listed on Sprout Health's site (checked August 28, 2026) |
| Brand-name | Yes | Yes |
| Oral option | Injectable only | Injectable only |
| Best for | The most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. | Patients who want a low compounded entry price but the option of brand-name Wegovy or Zepbound on the same account, with minimal onboarding. |
| Desk Score | 80/100B− | 86/100B |
The verdict
Desk pick — Sprout HealthSprout Health takes this head-to-head with the higher Desk Score, 86/100 (B) against 80/100 (B−) for Amazon One Medical. Amazon One Medical still holds its ground where its strengths line up with yours.
Choose Amazon One Medical if…
The most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings.
All 50 states
Choose Sprout Health if…
Patients who want a low compounded entry price but the option of brand-name Wegovy or Zepbound on the same account, with minimal onboarding.
$299/mo sema · $349/mo tirz
FDAWarning letter issued to Sprout Health Partners LLC dba Sprout Health in September 2025. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Amazon One Medical · Sprout Health.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- Amazon One Medical vs CoreAge Rx
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- AskRx vs Sprout Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.