Head-to-head comparison
Amazon One Medical vs CoreAge Rx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products).
Marked down on: Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
Desk Score
One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
$99/mo (12-month prepay) sema · $149/mo (12-month prepay) tirz · Verified August 2026
Marked down on: The advertised $99/$149 per month is a 12-month plan paid in full ($1,188 / $1,788 up front); no month-to-month price is published
CoreAge Rx takes this head-to-head with the higher Desk Score, 94/100 (A) against 85/100 (B) for Amazon One Medical. Amazon One Medical still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Amazon One Medical
85/100
B
CoreAge Rx
94/100
A
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Amazon One Medical | CoreAge Rx |
|---|---|---|
| Semaglutide | Not listed on Amazon One Medical's site (checked July 2026) | $99/mo12-month prepay$99/mo only as a 12-month plan paid in full ($1,188 in one charge); the lander says "starting at, based on a 12-month plan paid in full"; no month-to-month price is published; same price at every dose; compounded injectable |
| Tirzepatide | Not listed on Amazon One Medical's site (checked July 2026) | $149/mo12-month prepay$149/mo only as a 12-month plan paid in full ($1,788 in one charge); no month-to-month price is published; same price at every dose; compounded injectable |
| Coverage | All 50 states | All 50 states |
| Brand-name | Yes | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | The most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. | Anyone who can prepay a year and wants one dose-independent price with full nationwide reach. |
| Desk Score | 85/100B | 94/100A |
The verdict
Desk pick — CoreAge RxCoreAge Rx takes this head-to-head with the higher Desk Score, 94/100 (A) against 85/100 (B) for Amazon One Medical. Amazon One Medical still holds its ground where its strengths line up with yours.
Choose Amazon One Medical if…
The most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings.
All 50 states
Choose CoreAge Rx if…
Anyone who can prepay a year and wants one dose-independent price with full nationwide reach.
$99/mo (12-month prepay) sema · $149/mo (12-month prepay) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Amazon One Medical · CoreAge Rx.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.