Head-to-head dispatch
1st Optimal vs Tyde Wellness
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
Desk Score
Low entry pricing, oral options, and 50-state reach — a strong value pick for first-time GLP-1 patients.
Tyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 41/100 (C) for 1st Optimal. 1st Optimal still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
1st Optimal
41/100
C
Tyde Wellness
89/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | 1st Optimal | Tyde Wellness |
|---|---|---|
| Semaglutide | Not disclosed | $149/mo |
| Tirzepatide | Not disclosed | $249/mo |
| Coverage | Coverage not published | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. | First-timers who want an affordable, needle-optional on-ramp available anywhere in the country. |
| Desk Score | 41/100C | 89/100B+ |
The verdict
Desk pick — Tyde WellnessTyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 41/100 (C) for 1st Optimal. 1st Optimal still holds its ground where its strengths line up with yours.
Choose 1st Optimal if…
Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Not disclosed sema · Not disclosed tirz · Coverage not published
Choose Tyde Wellness if…
First-timers who want an affordable, needle-optional on-ramp available anywhere in the country.
$149/mo sema · $249/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: 1st Optimal · Tyde Wellness.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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- 1st Optimal vs Invigor Medical
- Tyde Wellness vs Vytora Health
Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.