Head-to-head dispatch
Sesame Care vs Synergy Rx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Desk Score
Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact.
Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 75/100 (C) for Synergy Rx. Synergy Rx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Sesame Care
87/100
B+
Synergy Rx
75/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Sesame Care | Synergy Rx |
|---|---|---|
| Semaglutide | From $149/mo (brand Wegovy pill) | From $199/mo |
| Tirzepatide | Brand Zepbound (price varies) | From $349/mo |
| Coverage | Nationwide marketplace | Not disclosed |
| Brand-name | Yes | Yes |
| Oral option | Yes | Injectable only |
| Best for | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. | People who want a brand-name lane and as much clinician access as possible, and will get pricing by enquiry. |
| Desk Score | 87/100B+ | 75/100C |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 75/100 (C) for Synergy Rx. Synergy Rx still holds its ground where its strengths line up with yours.
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace
Choose Synergy Rx if…
People who want a brand-name lane and as much clinician access as possible, and will get pricing by enquiry.
From $199/mo sema · From $349/mo tirz · Not disclosed
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Sesame Care · Synergy Rx.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Sesame Care vs CoreAge Rx
- Synergy Rx vs Vaylen
- Sesame Care vs Strut Health
- Synergy Rx vs Ondra Health
- Sesame Care vs Invigor Medical
- Synergy Rx vs Vytora Health
Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.