Head-to-head dispatch
Sesame Care vs SkinnyRx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Marked down on: A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
Desk Score
Both molecules by needle or by tablet, with the whole term ladder printed on the product page before any intake — and a headline rate that is the twelve-month rung, charged as one $2,388 payment on day one.
Marked down on: FDA issued Lean Rx, Inc. dba SkinnyRx a warning letter in February 2026; the letter is public in FDA's warning-letter database
FDAWarning letter issued to Lean Rx, Inc. dba SkinnyRx in February 2026. See the FDA warning-letter database.
Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 78/100 (C+) for SkinnyRx. SkinnyRx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Sesame Care
87/100
B+
SkinnyRx
78/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Sesame Care | SkinnyRx |
|---|---|---|
| Semaglutide | From $149/mo (brand Wegovy pill) | $349/mo month-to-month (compounded; the advertised rate is a 12-month prepay) |
| Tirzepatide | Brand Zepbound (price varies) | $399/mo month-to-month (compounded; the advertised rate is a 12-month prepay) |
| Coverage | Nationwide marketplace | 47 states + DC (not Alabama, Louisiana or Mississippi) |
| Brand-name | Yes | Compounded only |
| Oral option | Yes | Yes |
| Best for | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. | Readers who want a tablet route on either molecule and can pay a year up front; anyone shopping month to month should compare $349 and $399, not the advertised $199 and $299. |
| Desk Score | 87/100B+ | 78/100C+ |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 78/100 (C+) for SkinnyRx. SkinnyRx still holds its ground where its strengths line up with yours.
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace
Choose SkinnyRx if…
Readers who want a tablet route on either molecule and can pay a year up front; anyone shopping month to month should compare $349 and $399, not the advertised $199 and $299.
$349/mo month-to-month (compounded; the advertised rate is a 12-month prepay) sema · $399/mo month-to-month (compounded; the advertised rate is a 12-month prepay) tirz · 47 states + DC (not Alabama, Louisiana or Mississippi)
FDAWarning letter issued to Lean Rx, Inc. dba SkinnyRx in February 2026. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Sesame Care · SkinnyRx.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Sesame Care vs CoreAge Rx
- SkinnyRx vs Vaylen
- Sesame Care vs Strut Health
- SkinnyRx vs Ondra Health
- Sesame Care vs Invigor Medical
- SkinnyRx vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.