Head-to-head comparison
Science & Co vs Tyde Wellness
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Answers the question most sellers here never raise — it states in its own footer that it is not a compounding facility — and explains its own asterisk in its own FAQ.
$149/mo sema · $199/mo tirz · Verified September 2026
Marked down on: The number it leads with is a twelve-month commitment; the per-month rates are $149 and $199.
Desk Score
Compounded semaglutide from $149 a month and tirzepatide from $249, sold as a membership with nutrition coaching, a free consultation, and five named pharmacies — but no published dose ladder.
From $149/mo sema · From $249/mo tirz · Verified August 2026
Marked down on: No brand-name access
Tyde Wellness takes this head-to-head with the higher Desk Score, 90/100 (A−) against 76/100 (C) for Science & Co. Science & Co still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Science & Co
76/100
C
Tyde Wellness
90/100
A−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Science & Co | Tyde Wellness |
|---|---|---|
| Semaglutide | $149/mo$149/mo month-to-month (compounded; $79 only on a 12-month plan) | From $149/moFrom $149/mo, billed as a recurring membership (monthly or every 4 weeks); no dose ladder published; compounded injectable |
| Tirzepatide | $199/mo$199/mo month-to-month (compounded; $125 only on a 12-month plan) | From $249/moFrom $249/mo, billed as a recurring membership (monthly or every 4 weeks); no dose ladder published; compounded injectable |
| Coverage | Not listed on Science & Co's site (checked September 2026) | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | A twelve-month committer, or anyone who values a company stating plainly what it is and is not. | Someone who wants coaching and a clinician visit bundled with the prescription, and who will confirm the real monthly figure on the consult before enrolling. |
| Desk Score | 76/100C | 90/100A− |
The verdict
Desk pick — Tyde WellnessTyde Wellness takes this head-to-head with the higher Desk Score, 90/100 (A−) against 76/100 (C) for Science & Co. Science & Co still holds its ground where its strengths line up with yours.
Choose Science & Co if…
A twelve-month committer, or anyone who values a company stating plainly what it is and is not.
$149/mo sema · $199/mo tirz
Choose Tyde Wellness if…
Someone who wants coaching and a clinician visit bundled with the prescription, and who will confirm the real monthly figure on the consult before enrolling.
From $149/mo sema · From $249/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Science & Co · Tyde Wellness.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.