Head-to-head comparison
Renlo Health vs Spry
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
One of the few programs whose headline is the actual monthly rate, with the prescribing physician and the dispensing pharmacy both named.
$199/mo (see conditions) sema · $269/mo (see conditions) tirz · Verified September 2026
Marked down on: A struck-through $399 sits beside the price with no published basis — Renlo never says what it was, when it applied or to whom.
Desk Score
Spry is a weight-loss and anti-aging telehealth platform pairing compounded semaglutide ($199/mo) and tirzepatide ($299/mo) with three longevity peptides — BPC-157, NAD+, and sermorelin ($249–$299/mo).
From $199/mo (lowest dose rung) sema · From $299/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Displays an "FDA Approved" badge though compounded GLP-1s are not FDA-approved finished drugs — potentially misleading
Renlo Health takes this head-to-head with the higher Desk Score, 80/100 (B−) against 61/100 (C) for Spry. Spry still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Renlo Health
80/100
B−
Spry
61/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Renlo Health | Spry |
|---|---|---|
| Semaglutide | $199/mosee conditions$199/mo (compounded, billed monthly at every dose) | From $199/molowest dose rung$199/mo (starting dose, compounded) |
| Tirzepatide | $269/mosee conditions$269/mo (compounded, billed monthly at every dose) | From $299/molowest dose rung$299/mo (starting dose, compounded) |
| Coverage | Not listed on Renlo Health's site (checked September 2026) | Not listed on Spry's site (checked July 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Someone who wants a flat monthly bill, a named prescriber and a refund route, and can ignore an anchor nobody explains. | Compounded GLP-1 plus anti-aging peptides under one membership. |
| Desk Score | 80/100B− | 61/100C |
The verdict
Desk pick — Renlo HealthRenlo Health takes this head-to-head with the higher Desk Score, 80/100 (B−) against 61/100 (C) for Spry. Spry still holds its ground where its strengths line up with yours.
Choose Renlo Health if…
Someone who wants a flat monthly bill, a named prescriber and a refund route, and can ignore an anchor nobody explains.
$199/mo (see conditions) sema · $269/mo (see conditions) tirz
Choose Spry if…
Compounded GLP-1 plus anti-aging peptides under one membership.
From $199/mo (lowest dose rung) sema · From $299/mo (lowest dose rung) tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Renlo Health · Spry.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Renlo Health
- CoreAge Rx vs Spry
- HealthRX vs Renlo Health
- HealthRX vs Spry
- Renlo Health vs Welling Health
- Invigor Medical vs Spry
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.