Head-to-head comparison
Refills vs Trimi
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Refills (refills.com) is a LegitScript-certified online pharmacy and telehealth platform offering compounded GLP-1 weight-loss prescriptions (semaglutide, tirzepatide) alongside ED.
Marked down on: Ongoing monthly pricing for compounded semaglutide and tirzepatide not shown until after intake
FDAWarning letter issued to Refills Health, LLC dba Refills Health in February 2026. See the FDA warning-letter database.
Desk Score
Both molecules on one membership at a keen flat price, shipped free to all 50 states.
$175/mo sema · $235/mo tirz · Verified August 2026
Marked down on: Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
Trimi takes this head-to-head with the higher Desk Score, 88/100 (B+) against 54/100 (C) for Refills. Refills still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Refills
54/100
C
Trimi
88/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Refills | Trimi |
|---|---|---|
| Semaglutide | Not listed on Refills's site (checked June 2026) | $175/mo$175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge) |
| Tirzepatide | Not listed on Refills's site (checked June 2026) | $235/mo$235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge) |
| Coverage | Not listed on Refills's site (checked June 2026) | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Single account across GLP-1, ED and hair-growth telehealth. | Cost-first patients who want both molecules at the cheapest sticker price and don't need brand-name or oral routes. |
| Desk Score | 54/100C | 88/100B+ |
The verdict
Desk pick — TrimiTrimi takes this head-to-head with the higher Desk Score, 88/100 (B+) against 54/100 (C) for Refills. Refills still holds its ground where its strengths line up with yours.
Choose Refills if…
Single account across GLP-1, ED and hair-growth telehealth.
FDAWarning letter issued to Refills Health, LLC dba Refills Health in February 2026. See the FDA warning-letter database.
Choose Trimi if…
Cost-first patients who want both molecules at the cheapest sticker price and don't need brand-name or oral routes.
$175/mo sema · $235/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Refills · Trimi.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Refills
- CoreAge Rx vs Trimi
- Ondra Health vs Refills
- Trimi vs Vytora Health
- Refills vs Tyde Wellness
- HealthRX vs Trimi
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.