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Head-to-head dispatch

Primary Clinic (Direct GLP) vs yourEra

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #50
Primary Clinic (Direct GLP)

A Direct Primary Care membership rather than a GLP-1 storefront: the dose-band prices sit on top of an $89/mo membership the FAQ says does not include the drug.

$85/mo (0.25-0.75 mg band, membership required, compounded) sema · $133/mo (1.25-2.5 mg band, membership required, compounded) tirz

Marked down on: The medication price is on top of an $89/mo membership the FAQ says excludes the drug — all-in is about $174 and $222

vs
Dispatch #23Desk pick
yourEra

A compounded desk that advertises low floors — semaglutide from $79/mo, tirzepatide from $159/mo — with the plan price behind its intake, plus a NAD+ and microdosing menu, across all 50 states.

From $79/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) sema · From $159/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) tirz · Verified August 28, 2026

Marked down on: Compounded only — not FDA-approved and not equivalent to brand Wegovy/Ozempic or Zepbound; availability can tighten as brand shortages resolve

yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 80/100 (B−) for Primary Clinic (Direct GLP). Primary Clinic (Direct GLP) still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Primary Clinic (Direct GLP)

80/100

B−

Overall

yourEra

84/100

B

Price transparency

96
90

State access

62
92

Molecule range

80
84

Onboarding speed

78
80

Support responsiveness

76
80

Licensing & trust

72
78

The spec sheet

FieldPrimary Clinic (Direct GLP)yourEra
Semaglutide$85/mo (0.25-0.75 mg band, membership required, compounded)From $79/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded)
Tirzepatide$133/mo (1.25-2.5 mg band, membership required, compounded)From $159/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded)
CoverageWA, NM, AZ, UT, FL, DC, KS, OK, VA, GAAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forPatients in a covered state who want primary care bundled with the prescription and will price the membership in.Patients drawn by a low advertised floor on both semaglutide and tirzepatide who are willing to complete the intake to learn the plan price, value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.
Desk Score80/100B−84/100B

The verdict

Desk pick — yourEra

yourEra takes this head-to-head with the higher Desk Score, 84/100 (B) against 80/100 (B−) for Primary Clinic (Direct GLP). Primary Clinic (Direct GLP) still holds its ground where its strengths line up with yours.

Choose Primary Clinic (Direct GLP) if…

Patients in a covered state who want primary care bundled with the prescription and will price the membership in.

$85/mo (0.25-0.75 mg band, membership required, compounded) sema · $133/mo (1.25-2.5 mg band, membership required, compounded) tirz · WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA

Choose yourEra if…

Patients drawn by a low advertised floor on both semaglutide and tirzepatide who are willing to complete the intake to learn the plan price, value an add-on NAD+ or microdosing line, and don't need brand-name or oral routes.

From $79/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) sema · From $159/mo (a floor — yourera.com attaches no term, dose or billing cycle to it; the plan price is shown only after the intake quiz; compounded) tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Primary Clinic (Direct GLP) · yourEra.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.