Head-to-head comparison
Primary Clinic (Direct GLP) vs RxPepsDirect
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
A Direct Primary Care membership rather than a GLP-1 storefront: the dose-band prices sit on top of an $89/mo membership the FAQ says does not include the drug.
From $85/mo (lowest dose rung) sema · From $133/mo (lowest dose rung) tirz
Marked down on: The medication price is on top of an $89/mo membership the FAQ says excludes the drug — all-in is about $174 and $222
Desk Score
RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform whose advertised vial prices are not the whole cost.
From $79/mo (lowest dose rung) sema · From $99/mo (lowest dose rung) tirz · Verified August 2026
Marked down on: The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
Primary Clinic (Direct GLP) takes this head-to-head with the higher Desk Score, 79/100 (C+) against 66/100 (C) for RxPepsDirect. RxPepsDirect still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Primary Clinic (Direct GLP)
79/100
C+
RxPepsDirect
66/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Primary Clinic (Direct GLP) | RxPepsDirect |
|---|---|---|
| Semaglutide | From $85/molowest dose rung$85/mo (0.25-0.75 mg band, membership required, compounded) | From $79/molowest dose rung$79/mo (starting dose, visit fee and shipping included, compounded) |
| Tirzepatide | From $133/molowest dose rung$133/mo (1.25-2.5 mg band, membership required, compounded) | From $99/molowest dose rung$99/mo (starting dose, visit fee and shipping included, compounded) |
| Coverage | WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA | 28 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Patients in a covered state who want primary care bundled with the prescription and will price the membership in. | The all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states. |
| Desk Score | 79/100C+ | 66/100C |
The verdict
Desk pick — Primary Clinic (Direct GLP)Primary Clinic (Direct GLP) takes this head-to-head with the higher Desk Score, 79/100 (C+) against 66/100 (C) for RxPepsDirect. RxPepsDirect still holds its ground where its strengths line up with yours.
Choose Primary Clinic (Direct GLP) if…
Patients in a covered state who want primary care bundled with the prescription and will price the membership in.
From $85/mo (lowest dose rung) sema · From $133/mo (lowest dose rung) tirz · WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA
Choose RxPepsDirect if…
The all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.
From $79/mo (lowest dose rung) sema · From $99/mo (lowest dose rung) tirz · 28 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Primary Clinic (Direct GLP) · RxPepsDirect.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Primary Clinic (Direct GLP)
- CoreAge Rx vs RxPepsDirect
- Ondra Health vs Primary Clinic (Direct GLP)
- RxPepsDirect vs yourEra
- Effecty vs Primary Clinic (Direct GLP)
- RxPepsDirect vs Sunlight
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.