Head-to-head dispatch
Oak vs RxSpan MD
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
A wide menu — compounded, oral or brand-name — at $200/mo for compounded semaglutide and $250 for tirzepatide, from a seller that names its pharmacy and never auto-renews. The catch is that Oak's own FAQ says each dose step adds about $50 to $75, on the same page whose banner promises one price at every dosage.
$200/mo (compounded, list $250) on its own order form; Oak's FAQ says each dose step adds about $50 to $75, so this is a starting figure rather than a flat rate · oral semaglutide $245/mo · brand Ozempic $1,150/mo sema · $250/mo (compounded, list $300) on its own order form; Oak's FAQ says each dose step adds about $50 to $75, so this is a starting figure rather than a flat rate · brand Zepbound $1,250/mo, brand Mounjaro $1,100 per 4 weeks tirz · Verified August 29, 2026
Marked down on: The banner on Oak's own order form says "One price · All dosages" while the FAQ at the bottom of that same page says every dose step is "approximately $50 - $75 more" and that you agree in advance to pay whatever the doctor prescribes
Desk Score
A physician-founded desk with one of the widest menus in the ranking — compounded and brand-name GLP-1 across injectable and oral routes, microdosing, plus longevity, hair, and sexual-health lines — with transparent, all-inclusive pricing across all 50 states.
From $194/mo sema · $329/mo tirz
Marked down on: Compounded semaglutide and tirzepatide are not FDA-approved — not the same as Wegovy/Ozempic or Zepbound
RxSpan MD takes this head-to-head with the higher Desk Score, 86/100 (B) against 71/100 (C) for Oak. Oak still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Oak
71/100
C
RxSpan MD
86/100
B
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Oak | RxSpan MD |
|---|---|---|
| Semaglutide | $200/mo (compounded, list $250) on its own order form; Oak's FAQ says each dose step adds about $50 to $75, so this is a starting figure rather than a flat rate · oral semaglutide $245/mo · brand Ozempic $1,150/mo | From $194/mo |
| Tirzepatide | $250/mo (compounded, list $300) on its own order form; Oak's FAQ says each dose step adds about $50 to $75, so this is a starting figure rather than a flat rate · brand Zepbound $1,250/mo, brand Mounjaro $1,100 per 4 weeks | $329/mo |
| Coverage | 48 states (not West Virginia or Mississippi) | All 50 states |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | People who want compounded, oral or genuine brand-name access from one order form, will read that form rather than the advertising, and have budgeted for a bill that rises as the dose does. | Patients who want a broad, physician-led menu across GLP-1 routes and adjacent longevity care, with transparent all-inclusive pricing and nationwide reach. |
| Desk Score | 71/100C | 86/100B |
The verdict
Desk pick — RxSpan MDRxSpan MD takes this head-to-head with the higher Desk Score, 86/100 (B) against 71/100 (C) for Oak. Oak still holds its ground where its strengths line up with yours.
Choose Oak if…
People who want compounded, oral or genuine brand-name access from one order form, will read that form rather than the advertising, and have budgeted for a bill that rises as the dose does.
$200/mo (compounded, list $250) on its own order form; Oak's FAQ says each dose step adds about $50 to $75, so this is a starting figure rather than a flat rate · oral semaglutide $245/mo · brand Ozempic $1,150/mo sema · $250/mo (compounded, list $300) on its own order form; Oak's FAQ says each dose step adds about $50 to $75, so this is a starting figure rather than a flat rate · brand Zepbound $1,250/mo, brand Mounjaro $1,100 per 4 weeks tirz · 48 states (not West Virginia or Mississippi)
Choose RxSpan MD if…
Patients who want a broad, physician-led menu across GLP-1 routes and adjacent longevity care, with transparent all-inclusive pricing and nationwide reach.
From $194/mo sema · $329/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Oak · RxSpan MD.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Oak
- CoreAge Rx vs RxSpan MD
- Oak vs Vaylen
- RxSpan MD vs Vaylen
- Oak vs Semaglutide Online
- RxSpan MD vs Semaglutide Online
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.