Head-to-head dispatch
NewSelf vs TRYM Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo).
Marked down on: Not available in Mississippi and Louisiana
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Desk Score
TRYM Health (TRYM) is a nationwide telehealth service offering compounded GLP-1 weight-loss medication — semaglutide (~$96/mo, $3.20/day) and tirzepatide (~$126/mo, $4.20/day) — as additive-free multi-dose…
Marked down on: Compounding pharmacy partner not named
FDAWarning letter issued to TRYM Health, Inc. dba TRYM Health in September 2025. See the FDA warning-letter database.
NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 66/100 (C) for TRYM Health. TRYM Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
NewSelf
79/100
C+
TRYM Health
66/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | NewSelf | TRYM Health |
|---|---|---|
| Semaglutide | $100/mo (compounded) | $96/mo (all doses, compounded) |
| Tirzepatide | $144/mo (compounded) | $126/mo (all doses, compounded) |
| Coverage | 49 states | Coverage not published |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Readers who want lowest-cost compounded GLP-1 with pharmacy quality transparency. | Readers who want budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide. |
| Desk Score | 79/100C+ | 66/100C |
The verdict
Desk pick — NewSelfNewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 66/100 (C) for TRYM Health. TRYM Health still holds its ground where its strengths line up with yours.
Choose NewSelf if…
Readers who want lowest-cost compounded GLP-1 with pharmacy quality transparency.
$100/mo (compounded) sema · $144/mo (compounded) tirz · 49 states
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Choose TRYM Health if…
Readers who want budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide.
$96/mo (all doses, compounded) sema · $126/mo (all doses, compounded) tirz · Coverage not published
FDAWarning letter issued to TRYM Health, Inc. dba TRYM Health in September 2025. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: NewSelf · TRYM Health.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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- NewSelf vs Invigor Medical
- TRYM Health vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.