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Head-to-head comparison

NewSelf vs TRYM Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Ranked #72Desk pick
NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo).

$100/mo sema · $144/mo tirz · Verified July 2026

Marked down on: Not available in Mississippi and Louisiana

FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.

vs
Ranked #227
TRYM Health

TRYM Health (TRYM) is a nationwide telehealth service offering compounded GLP-1 weight-loss medication — semaglutide (~$96/mo, $3.20/day) and tirzepatide (~$126/mo, $4.20/day).

$96/mo sema · $126/mo tirz · Verified June 2026

Marked down on: Compounding pharmacy partner not named

FDAWarning letter issued to TRYM Health, Inc. dba TRYM Health in September 2025. See the FDA warning-letter database.

NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 66/100 (C) for TRYM Health. TRYM Health still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

NewSelf

79/100

C+

Overall

TRYM Health

66/100

C

Price transparency

86
94

State access

78
24

Molecule range

66
66

Onboarding speed

84
77

Support responsiveness

84
77

Licensing & trust

71
52

The spec sheet

FieldNewSelfTRYM Health
Semaglutide$100/mo$100/mo (compounded)$96/mo$96/mo (all doses, compounded)
Tirzepatide$144/mo$144/mo (compounded)$126/mo$126/mo (all doses, compounded)
Coverage49 statesNot listed on TRYM Health's site (checked June 2026)
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forLowest-cost compounded GLP-1 with pharmacy quality transparency.Budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide.
Desk Score79/100C+66/100C

The verdict

Desk pick — NewSelf

NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 66/100 (C) for TRYM Health. TRYM Health still holds its ground where its strengths line up with yours.

Choose NewSelf if…

Lowest-cost compounded GLP-1 with pharmacy quality transparency.

$100/mo sema · $144/mo tirz · 49 states

FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.

Choose TRYM Health if…

Budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide.

$96/mo sema · $126/mo tirz

FDAWarning letter issued to TRYM Health, Inc. dba TRYM Health in September 2025. See the FDA warning-letter database.

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: NewSelf · TRYM Health.

Also here

CoreAge Rx leads the whole ranking at 94/100

Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.