Head-to-head comparison
NewSelf vs Pepti
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo).
$100/mo sema · $144/mo tirz · Verified July 2026
Marked down on: Not available in Mississippi and Louisiana
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Desk Score
Pepti prices both molecules openly at $109 and $179, publishes a page for every state it serves, and runs a 28-day cycle its own terms say can bill twice in one calendar month.
From $109/mo sema · From $179/mo tirz · Verified September 2026
Marked down on: The cycle is 28 days, and the billing terms say it can charge twice in the same calendar month while the product pages call the figure an all-in monthly price.
NewSelf and Pepti land level on the Desk Score at 79/100 — too close to call. The right choice comes down to which trade-offs fit your situation.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
NewSelf
79/100
C+
Pepti
79/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | NewSelf | Pepti |
|---|---|---|
| Semaglutide | $100/mo$100/mo (compounded) | From $109/moFrom $109/mo (28-day cycle, compounded) |
| Tirzepatide | $144/mo$144/mo (compounded) | From $179/moFrom $179/mo (28-day cycle, compounded) |
| Coverage | 49 states | All 50 states and D.C. |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Lowest-cost compounded GLP-1 with pharmacy quality transparency. | Anyone who wants one all-in figure with nothing layered on top, and will read the billing cycle. |
| Desk Score | 79/100C+ | 79/100C+ |
The verdict
Too close to callNewSelf and Pepti land level on the Desk Score at 79/100 — too close to call. The right choice comes down to which trade-offs fit your situation.
Choose NewSelf if…
Lowest-cost compounded GLP-1 with pharmacy quality transparency.
$100/mo sema · $144/mo tirz · 49 states
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Choose Pepti if…
Anyone who wants one all-in figure with nothing layered on top, and will read the billing cycle.
From $109/mo sema · From $179/mo tirz · All 50 states and D.C.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: NewSelf · Pepti.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs NewSelf
- CoreAge Rx vs Pepti
- NewSelf vs Sunlight
- Pepti vs Sunlight
- NewSelf vs Vitara RX
- EverSlim vs Pepti
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.