Head-to-head comparison
LifeMD vs Sesame Care
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Publicly traded telehealth provider offering brand-name GLP-1 medications only.
Marked down on: Brand-name GLP-1 only — no lower-cost compounded option
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
$149/mo (brand-name) sema · $299/mo (brand-name) tirz · Verified August 2026
Marked down on: A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
Sesame Care takes this head-to-head with the higher Desk Score, 88/100 (B+) against 63/100 (C) for LifeMD. LifeMD still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
LifeMD
63/100
C
Sesame Care
88/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | LifeMD | Sesame Care |
|---|---|---|
| Semaglutide | Not listed on LifeMD's site (checked July 2026) | $149/mobrand-nameBrand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg; brand Wegovy and Ozempic injections $199/mo for the first two months at the lowest strengths, then $349/mo — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) |
| Tirzepatide | Not listed on LifeMD's site (checked July 2026) | $299/mobrand-nameBrand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg); the weight-loss program page prints a THIRD ladder for the same drug at $299 / $398 / $499 / $698 — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days |
| Coverage | All 50 states | Nationwide marketplace |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Non-GLP-1 weight management. | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. |
| Desk Score | 63/100C | 88/100B+ |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 88/100 (B+) against 63/100 (C) for LifeMD. LifeMD still holds its ground where its strengths line up with yours.
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
$149/mo (brand-name) sema · $299/mo (brand-name) tirz · Nationwide marketplace
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: LifeMD · Sesame Care.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs LifeMD
- CoreAge Rx vs Sesame Care
- LifeMD vs RxSpan MD
- Sesame Care vs Strut Health
- LifeMD vs Shed
- Ondra Health vs Sesame Care
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.